足底肢端黑色素瘤：流行病学、临床、皮肤镜和组织病理学特征。一群巴西人。

IF 2.6 4区医学 Q2 DERMATOLOGY

Anais brasileiros de dermatologia Pub Date : 2025-01-01 DOI:10.1016/j.abd.2024.03.006

Lucas Campos Garcia , João Renato Vianna Gontijo , Flávia Vasques Bittencourt

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引用次数: 0

摘要

背景：肢端黑色素瘤（AM）是罕见的，大约三分之二发生在脚底，在黑人和亚洲人中更为普遍。在巴西人群中，关于这种黑色素瘤亚型的数据很少。目的：描述和关联AM的流行病学、临床、皮肤镜和组织病理学特征。方法：单中心、回顾性和横断面研究，评估15年的数据。结果：共纳入48例。平均年龄62.54岁，以女性居多（62.5%）。肤色较浅的患者无色素黑素瘤的比例较高（20% × 7.7%）。多色症是最普遍的发现（94.4%）。平行脊型（PRP）患病率为78%，锯齿型与较低的Breslow厚度相关（p = 0.041）。组织病理学（p = 0.013）或皮肤镜（p = 0.047）评估的溃疡与较大的Breslow厚度相关。研究局限性：有资料缺失的回顾性研究。结论：无色素瘤在浅色光型中发病率较高（20% × 7.7%）。多色症是最常见的发现（94.4%），临床或组织病理学评估中观察到的溃疡与较高的Breslow厚度相关（p = 0.013和0.047）。

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Plantar acral melanoma: epidemiological, clinical, dermoscopic and histopathological features. A Brazilian cohort

Background

Acral melanomas (AM) are rare and approximately two-thirds of them occur on the soles of the feet beeing more prevalent in black and Asian individuals. Data on this subtype of melanoma are scarce in the Brazilian population.

Objectives

To describe and correlate the epidemiological, clinical, dermoscopic, and histopathological features of AM a.

Methods

Single-center, retrospective and cross-sectional study, evaluating data from a 15-year period.

Results

A total of 48 cases were included. Mean age was 62.54 years, with a predominance of women (62.5%). The percentage of amelanotic melanomas was higher among lighter skin patients (20% × 7.7%). Polychromia was the most prevalent finding (94.4%). The parallel ridge pattern (PRP) had a prevalence of 78% and a serrated pattern was associated with lower Breslow thickness (p = 0.041). Ulceration present on histopathological (p = 0.013) or dermoscopic (p = 0.047) evaluation was associated with greater Breslow thickness.

Study limitations

Retrospective study with loss of data.

Conclusion

Amelanotic tumors were more prevalent in ligther phototypes (20% × 7.7%). Polychromia was the most prevalent finding (94.4%) and ulceration observed on clinical or histopathological evaluation was associated with higher Breslow thickness (p = 0.013 and 0.047).

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来源期刊

Anais brasileiros de dermatologia DERMATOLOGY-

CiteScore

2.40

自引率

0.00%

发文量

184

审稿时长

32 days

期刊介绍： The journal is published bimonthly and is devoted to the dissemination of original, unpublished technical-scientific study, resulting from research or reviews of dermatological topics and related matters. Exchanges with other publications may be accepted.