{"title":"不受抑制的癌症免疫会引发动脉粥样硬化。","authors":"Jesse W. Williams, Esther Lutgens","doi":"10.1038/s44161-024-00571-4","DOIUrl":null,"url":null,"abstract":"Researchers map the expression of immune checkpoints and cell interactions within human atherosclerotic plaques, and the influence of relevant comorbidities such as dyslipidemia and diabetes. The findings shed light on the potential mechanisms behind the increased risk of cardiovascular events after treatment with immune checkpoint inhibitors.","PeriodicalId":74245,"journal":{"name":"Nature cardiovascular research","volume":"3 12","pages":"1380-1382"},"PeriodicalIF":9.4000,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Unrestrained cancer immunity ignites atherosclerosis\",\"authors\":\"Jesse W. Williams, Esther Lutgens\",\"doi\":\"10.1038/s44161-024-00571-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Researchers map the expression of immune checkpoints and cell interactions within human atherosclerotic plaques, and the influence of relevant comorbidities such as dyslipidemia and diabetes. The findings shed light on the potential mechanisms behind the increased risk of cardiovascular events after treatment with immune checkpoint inhibitors.\",\"PeriodicalId\":74245,\"journal\":{\"name\":\"Nature cardiovascular research\",\"volume\":\"3 12\",\"pages\":\"1380-1382\"},\"PeriodicalIF\":9.4000,\"publicationDate\":\"2024-11-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature cardiovascular research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.nature.com/articles/s44161-024-00571-4\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature cardiovascular research","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s44161-024-00571-4","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Unrestrained cancer immunity ignites atherosclerosis
Researchers map the expression of immune checkpoints and cell interactions within human atherosclerotic plaques, and the influence of relevant comorbidities such as dyslipidemia and diabetes. The findings shed light on the potential mechanisms behind the increased risk of cardiovascular events after treatment with immune checkpoint inhibitors.