绘制人类肠道衍生的Blautia菌的基因组,该菌可改善小鼠结肠炎和结肠炎相关的社交缺陷。

IF 0.7 Q4 MICROBIOLOGY
Microbiology Resource Announcements Pub Date : 2025-01-16 Epub Date: 2024-11-29 DOI:10.1128/mra.00726-24
Michaela A Murphy, D Garrett Brown, Rickesha S Bell, Allison M Weis, Logan A Barrios, W Zac Stephens, June L Round
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引用次数: 0

摘要

Blautia是一种厌氧革兰氏阳性细菌属,常见于哺乳动物胃肠道。然而,人们对不同蓝菌菌株之间的差异如何影响宿主健康知之甚少。我们提出了从人类粪便中分离的Blautia sp基因组,将其补充给小鼠可以改善结肠炎的严重程度和相关的社交缺陷。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Draft genome of a human gut-derived Blautia sp. that ameliorates colitis and colitis-associated sociability deficits in mice.

Blautia is a genus of anaerobic, gram-positive bacteria commonly found in mammalian gastrointestinal tracts. Yet, how variations among different Blautia strains can impact host health is poorly understood. We present a Blautia sp. genome isolated from human feces whose supplementation to mice can ameliorate colitis severity and associated sociability deficits.

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来源期刊
CiteScore
1.50
自引率
12.50%
发文量
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