Michaela A Murphy, D Garrett Brown, Rickesha S Bell, Allison M Weis, Logan A Barrios, W Zac Stephens, June L Round
{"title":"绘制人类肠道衍生的Blautia菌的基因组,该菌可改善小鼠结肠炎和结肠炎相关的社交缺陷。","authors":"Michaela A Murphy, D Garrett Brown, Rickesha S Bell, Allison M Weis, Logan A Barrios, W Zac Stephens, June L Round","doi":"10.1128/mra.00726-24","DOIUrl":null,"url":null,"abstract":"<p><p><i>Blautia</i> is a genus of anaerobic, gram-positive bacteria commonly found in mammalian gastrointestinal tracts. Yet, how variations among different <i>Blautia</i> strains can impact host health is poorly understood. We present a <i>Blautia</i> sp. genome isolated from human feces whose supplementation to mice can ameliorate colitis severity and associated sociability deficits.</p>","PeriodicalId":18654,"journal":{"name":"Microbiology Resource Announcements","volume":" ","pages":"e0072624"},"PeriodicalIF":0.7000,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11737165/pdf/","citationCount":"0","resultStr":"{\"title\":\"Draft genome of a human gut-derived <i>Blautia</i> sp. that ameliorates colitis and colitis-associated sociability deficits in mice.\",\"authors\":\"Michaela A Murphy, D Garrett Brown, Rickesha S Bell, Allison M Weis, Logan A Barrios, W Zac Stephens, June L Round\",\"doi\":\"10.1128/mra.00726-24\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><i>Blautia</i> is a genus of anaerobic, gram-positive bacteria commonly found in mammalian gastrointestinal tracts. Yet, how variations among different <i>Blautia</i> strains can impact host health is poorly understood. We present a <i>Blautia</i> sp. genome isolated from human feces whose supplementation to mice can ameliorate colitis severity and associated sociability deficits.</p>\",\"PeriodicalId\":18654,\"journal\":{\"name\":\"Microbiology Resource Announcements\",\"volume\":\" \",\"pages\":\"e0072624\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-01-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11737165/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Microbiology Resource Announcements\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1128/mra.00726-24\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/11/29 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microbiology Resource Announcements","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1128/mra.00726-24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/11/29 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
Draft genome of a human gut-derived Blautia sp. that ameliorates colitis and colitis-associated sociability deficits in mice.
Blautia is a genus of anaerobic, gram-positive bacteria commonly found in mammalian gastrointestinal tracts. Yet, how variations among different Blautia strains can impact host health is poorly understood. We present a Blautia sp. genome isolated from human feces whose supplementation to mice can ameliorate colitis severity and associated sociability deficits.