新型武器炸药在植物中表现出持久的毒性。

IF 15.8 1区生物学 Q1 PLANT SCIENCES

Nature Plants Pub Date : 2024-11-28 DOI:10.1038/s41477-024-01863-0

Nicola C. Oates, Edward R. Nay, Timothy J. Cary, Elizabeth L. Rylott, Neil C. Bruce

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引用次数: 0

摘要

爆炸物是广泛存在的、有毒的、持久性的环境污染物。2,4-二硝基甲苯（DNAN）正在逐步取代弹药中的2,4,6-三硝基甲苯（TNT）。在这里，我们证明只有低水平的DNAN在拟南芥中被解毒，使其仍然作为单脱氢抗坏血酸还原酶6介导的慢性植物毒性的底物。增强环境毒性的可能性，DNAN很容易被运输到空中组织，使这种毒素暴露于食草动物和更广泛的食物链。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

New weapons explosive exhibits persistent toxicity in plants

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New weapons explosive exhibits persistent toxicity in plants

Explosives are widespread, toxic and persistent environmental pollutants. 2,4-Dinitroanisole (DNAN) is being phased in to replace 2,4,6-trinitrotoluene (TNT) in munitions. Here we demonstrate that only low levels of DNAN are detoxified in Arabidopsis, leaving it to remain as a substrate for monodehydroascorbate reductase 6 mediated chronic phytotoxicity. Enhancing the potential for environmental toxicity, DNAN is readily transported to the aerial tissues exposing this toxin to herbivores and the wider food chain. This study reports the mechanism of phytotoxicity by the explosive 2,4-dinitroanisole (DNAN) that is being phased in to replace TNT in munitions. Only low levels of DNAN are detoxified by plants, causing chronic toxicity and potential exposure to herbivores.

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来源期刊

Nature Plants PLANT SCIENCES-

CiteScore

25.30

自引率

2.20%

发文量

196

期刊介绍： Nature Plants is an online-only, monthly journal publishing the best research on plants — from their evolution, development, metabolism and environmental interactions to their societal significance.