美国中老年成年人健康生活方式行为与全因死亡风险的结合：一项纵向队列研究

IF 3.5 3区医学 Q2 GERIATRICS & GERONTOLOGY

Archives of gerontology and geriatrics Pub Date : 2024-11-24 DOI:10.1016/j.archger.2024.105702

Luyao Qiao, Yan Wang, Yi Deng, Jiaxing Peng, Yanping Li, Min Li, Zhenyu Tang

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引用次数: 0

摘要

虽然各种生活方式行为单独或部分地被证明与健康结果相关，包括多种疾病和死亡，但早期的研究都没有全面调查改变生活方式行为的综合影响。这项纵向研究调查了健康生活方式行为与中老年美国人全因死亡率之间的关系。方法利用2007 - 2018年全国健康与营养调查数据以及相关死亡率数据，应用健康生活方式评分（HLS）指数评估健康生活方式行为，不吸烟、适度饮酒、适当睡眠、均衡饮食、充足的身体活动和有限的久坐时间。采用加权多变量Cox比例风险分析来调查这些生活方式与总体死亡率之间的关系，然后进行分层分析以探索亚组的潜在影响改变。结果本研究纳入5448名受试者，分为HLS不良组（28%）、中度组（56%）和良好组（16%）。在中位103个月的随访期间，388名参与者死亡。Cox回归显示，生活方式良好的个体比生活方式不良的个体死亡的可能性低（HR = 0.49, 95% CI: 0.34-0.70）。HLS与全因死亡似然呈线性负相关（非线性p = 0.0512）。结论：在美国，坚持健康习惯与降低老年人全因死亡率的可能性呈线性和实质性关系，强调了保持这些行为对长寿和健康的实质性好处。

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查看原文本刊更多论文

Combined healthy lifestyle behaviors and all-cause mortality risk in middle-aged and older US adults: A longitudinal cohort study

Background

While various lifestyle behaviors separately or partly have been shown to be associated with health outcomes, including a multitude of diseases and death, none of the earlier research has comprehensively investigated the combined impact of modified lifestyle behaviors. This longitudinal study investigated the association between a composite of healthy lifestyle behaviors and all-cause mortality in middle-aged and older Americans.

Methods

We utilized data from the National Health and Nutrition Examination Survey from 2007 to 2018, as well as relevant mortality data, applying the Healthy Lifestyle Score¹ (HLS) index to assess healthy lifestyle behaviors, defined by no smoking, moderate alcohol, appropriate sleep, a balanced diet, adequate physical activity, and limited sedentary time. Weighted multivariate Cox proportional hazards analyses were applied to investigate the associations between these lifestyle practices and overall mortality, followed by stratified analyses to explore potential effect modifications by subgroups.

Results

This study included 5448 participants, categorized into unfavorable (28%), intermediate (56%), and favorable (16%) HLS groups. During a median 103-month follow-up, 388 participants died. Cox regression revealed that individuals with favorable lifestyles had a reduced likelihood of death than those with unfavorable lifestyles (HR = 0.49, 95% CI: 0.34–0.70). There was a linear negative relationship established between HLS and the likelihood of all-cause death (p for non-linearity = 0.0512).

Conclusion

Adherence to a composite of healthy habits is linearly and substantially related to decreasing the likelihood of all-cause mortality among the elderly in the U.S., highlighting the substantial benefits of maintaining these behaviors for longevity and health.

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来源期刊

Archives of gerontology and geriatrics 医学-老年医学

CiteScore

7.30

自引率

5.00%

发文量

198

审稿时长

16 days

期刊介绍： Archives of Gerontology and Geriatrics provides a medium for the publication of papers from the fields of experimental gerontology and clinical and social geriatrics. The principal aim of the journal is to facilitate the exchange of information between specialists in these three fields of gerontological research. Experimental papers dealing with the basic mechanisms of aging at molecular, cellular, tissue or organ levels will be published. Clinical papers will be accepted if they provide sufficiently new information or are of fundamental importance for the knowledge of human aging. Purely descriptive clinical papers will be accepted only if the results permit further interpretation. Papers dealing with anti-aging pharmacological preparations in humans are welcome. Papers on the social aspects of geriatrics will be accepted if they are of general interest regarding the epidemiology of aging and the efficiency and working methods of the social organizations for the health care of the elderly.