单细胞基因组学在细胞周期检测方面开辟了新天地

IF 31.7 1区生物学 Q1 GENETICS & HEREDITY

Nature genetics Pub Date : 2024-11-29 DOI:10.1038/s41588-024-01987-1

Qian Du

引用次数: 0

摘要

一种分析单细胞基因组学的新方法可以直接推断细胞周期和增殖状态，突出克隆癌中增殖率的多样性。这种方法为在单细胞水平上探索增殖在癌症进化中的作用开辟了一条高分辨率的新途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Single-cell genomics breaks new ground in cell cycle detection

查看原文本刊更多论文

Single-cell genomics breaks new ground in cell cycle detection

A novel method for analyzing single-cell genomics enables direct inference of cell cycle and proliferation status, highlighting the diversity of proliferation rates in clonal cancer. This approach opens a new avenue for high-resolution exploration of the role of proliferation in cancer evolution at the single-cell level.

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来源期刊

Nature genetics 生物-遗传学

CiteScore

43.00

自引率

2.60%

发文量

241

审稿时长

3 months

期刊介绍： Nature Genetics publishes the very highest quality research in genetics. It encompasses genetic and functional genomic studies on human and plant traits and on other model organisms. Current emphasis is on the genetic basis for common and complex diseases and on the functional mechanism, architecture and evolution of gene networks, studied by experimental perturbation. Integrative genetic topics comprise, but are not limited to: -Genes in the pathology of human disease -Molecular analysis of simple and complex genetic traits -Cancer genetics -Agricultural genomics -Developmental genetics -Regulatory variation in gene expression -Strategies and technologies for extracting function from genomic data -Pharmacological genomics -Genome evolution