桉树(Eucalyptus camaldulensis)用于抗击多重抗药性菌株(MDRS)。

Q2 Agricultural and Biological Sciences
Brazilian Journal of Biology Pub Date : 2024-11-22 eCollection Date: 2024-01-01 DOI:10.1590/1519-6984.282826
H M Taj, F Zubair, N Riaz, S Taj, N Amjad, A Iqbal, R Afzal, A Ghaffar, S Kiran, M I U Saleemi
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引用次数: 0

摘要

细菌的抗生素耐药性是全球健康面临的首要挑战。由于使用储存食品而导致食物中毒的情况与日俱增。本研究旨在研究桉树甲醇提取物对选定菌株(大肠杆菌、蜡样芽孢杆菌、枯草杆菌和金黄色葡萄球菌)的保护作用。处理过程中使用了多种浓度,然后根据温度和酸碱度的变化进行表征。通过 MIC(最低抑菌浓度)观察对这些菌株的抑制效果。结果表明,在 250 毫克/毫升的浓度下,E. camaldulensis 对大肠杆菌的抑制作用最大(5.6 毫米),而在 200 毫克/毫升的浓度下,E. camaldulensis 对蜡样芽孢杆菌的抑制作用为 3.6 毫米,在 250 毫克/毫升的浓度下,金黄色葡萄球菌的抑制区最大(3.1 毫米)。对其他菌株的研究结果表明,121 °C时对枯草杆菌的最大作用区为5.7毫米,80 °C时对金黄色葡萄球菌的最大作用区为6.6毫米。通过改变 pH 值观察结果发现,7pH 时对蜡样芽孢杆菌产生的 MIC 为 6.2 毫米,5pH 时对枯草芽孢杆菌的抑制区为 7.2 毫米,3pH 时对大肠杆菌的抑制区为 5.4 毫米。所有不同变量(浓度、pH 值和温度)的结果均值均采用单因素方差分析进行比较。目前的研究表明,E. camaldulensis 的甲醇提取物能有效控制抗生素耐药菌株,这项研究加强了使用草药溶液控制抗生素耐药细菌感染的事实。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Eucalyptus camaldulensis for combating the Multi Drug Resistance Bacterial Strains (MDRS).

Antibiotic resistance in bacteria is the primary challenge for health worldwide. The widespread of food poisoning due to use of stored food items increasing day by day. The present study was designed to research the protective effect of Eucalyptus camaldulensis methanolic extract again selected strains of bacteria (Escherichia coli, Bacillus cereus, Bacillus subtilis and Staphylococcus aureus). The treatment was used for several concentrations and then characterized on the basis of temperature and pH variations. Results were observed by MIC (minimum inhibitory concentration) against these strains. It was noted that maximum inhibition of E. camaldulensis against E.coli (5.6mm) was observed at 250 mg/mL while it was 3.6mm against B. cereus at 200 mg/mL, Staph. aureus showed maximum (3.1mm) zone at 250 mg/mL. at variable temperature of E. camaldulensis extract, it was observed that MIC of B. cereus was 6.4mm at 80 °C. For other strains the results revealed that the maximum zone against B. subtilis was 5.7mm at 121 °C and for Staph. aureus it was 6.6mm at 80 °C. By observing the results by changing pH it was observed that MIC produced against B. cereus was 6.2mm at 7pH, against B. subtilis zone of inhibition was 7.2mm at 5pH, for E.coli it was 5.4mm at 3pH. Means of all the variable results of different (concentration, pH and temperature) were compared by using one way ANOVA. The current study suggested that the methanolic extract of E. camaldulensis was found effective in control of antibiotic resistant strains and this study strengthens the fact of using herbal solutions for control of antibiotic resistant bacterial infections.

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来源期刊
CiteScore
2.40
自引率
0.00%
发文量
301
审稿时长
4-8 weeks
期刊介绍: The BJB – Brazilian Journal of Biology® is a scientific journal devoted to publishing original articles in all fields of the Biological Sciences, i.e., General Biology, Cell Biology, Evolution, Biological Oceanography, Taxonomy, Geographic Distribution, Limnology, Aquatic Biology, Botany, Zoology, Genetics, and Ecology. Priority is given to papers presenting results of researches in the Neotropical region. Material published includes research papers, review papers (upon approval of the Editorial Board), notes, book reviews, and comments.
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