代谢综合征和低无脂肪量是否会缩短一个人的无残疾寿命?韩国基因组与流行病学研究(KoGES)的一项为期 12 年的前瞻性队列研究。

IF 1.7 4区 医学 Q2 NURSING
Ji Hye Shin, Ju Young Yoon
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引用次数: 0

摘要

研究目的本研究旨在探讨代谢综合征(MetS)和低去脂体重(FFM)对个体无残疾生存期(DFS)的综合风险。残疾的定义是痴呆、身体残疾和死亡率的综合:利用韩国基因组与流行病学研究的数据,我们根据 MetS 状态和 FFM 指数(FFMI)得分对 3721 名 40-69 岁的参与者进行了划分。采用卡普兰-米尔生存分析和 Cox 回归分析四组间 DFS 的差异:结果:在 108 个事件中,MetS 组的 DFS 明显短于非 MetS 组,与 FFMI 无关(p 结论:MetS 组的 DFS 明显高于非 MetS 组:MetS 和低 FFMI 的组合会导致 DFS 缩短的累积风险。社区护士可以进行 MetS 筛查和身体成分评估,以预测和控制随着时间推移出现残疾的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Does the Combination of Metabolic Syndrome and Low Fat-Free Mass Shorten an Individual's Disability-Free Life? A 12-Year Prospective Cohort Study of the Korean Genome and Epidemiology Study (KoGES).

Objective: This study aims to explore the combined risk of metabolic syndrome (MetS) and low fat-free mass (FFM) on an individual's disability-free survival (DFS). Disability is defined as a composite of dementia, physical disability, and mortality.

Methods: Using data from the Korean Genome and Epidemiology Study, we divided 3721 participants aged 40-69 years based on their MetS status and FFM index (FFMI) score. Kaplan-Meier survival analysis and Cox regression were used to analyze differences in DFS between the four groups.

Results: From 108 events, MetS group had significantly shorter DFS than the non-MetS group regardless of FFMI (p < 0.0001). After adjusting other potential confounding variables, the MetS group had a higher risk of shortened DFS regardless of FFMI, and the MetS group with low FFMI had a 2.06-fold increased risk compared to the non-MetS group with high FFMI (p < 0.001). Older age and lower income were also associated with higher risk of shorter DFS (p < 0.001).

Conclusions: The combination of MetS and low FFMI contribute to a cumulative risk of shortened DFS. Community nurses can perform MetS screening and body composition assessment to predict and control the risk of developing disability over time.

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来源期刊
Public Health Nursing
Public Health Nursing 医学-公共卫生、环境卫生与职业卫生
CiteScore
3.50
自引率
4.80%
发文量
117
审稿时长
6-12 weeks
期刊介绍: Public Health Nursing publishes empirical research reports, program evaluations, and case reports focused on populations at risk across the lifespan. The journal also prints articles related to developments in practice, education of public health nurses, theory development, methodological innovations, legal, ethical, and public policy issues in public health, and the history of public health nursing throughout the world. While the primary readership of the Journal is North American, the journal is expanding its mission to address global public health concerns of interest to nurses.
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