乌干达北部里拉地区胎盘疟疾的发病率和相关因素:一项横断面研究。

IF 2.4 3区 医学 Q3 INFECTIOUS DISEASES
Joshua Epuitai, Grace Ndeezi, Rose Chalo Nabirye, Lydia Kabiri, David Mukunya, Josephine Tumuhamye, Faith Oguttu, James K Tumwine
{"title":"乌干达北部里拉地区胎盘疟疾的发病率和相关因素:一项横断面研究。","authors":"Joshua Epuitai, Grace Ndeezi, Rose Chalo Nabirye, Lydia Kabiri, David Mukunya, Josephine Tumuhamye, Faith Oguttu, James K Tumwine","doi":"10.1186/s12936-024-05187-4","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Malaria has a stable perennial transmission across Uganda. Placental malaria is associated with adverse maternal, fetal, and neonatal outcomes. The factors associated with placental malaria are poorly understood in the study setting. The aim of the study was to assess the prevalence of placental malaria and to determine its associated factors among parturient women in Lira District, Uganda.</p><p><strong>Methods: </strong>This was a cross-sectional study among 366 pregnant women who delivered at Lira Regional Referral Hospital. Data were collected from December 2018 to February 2019 using an interviewer-administered questionnaire. The variables were socio-demographic, obstetric characteristics, and malaria preventive practices. Standard Diagnostic Bioline Rapid Diagnostic Tests were used to detect placental malaria present in placental blood. Microscopy was used to quantify the grade of placental malaria parasitaemia. Logistic regression was used to assess factors associated with placental malaria.</p><p><strong>Results: </strong>The mean age of the participants was 25.34 years (standard deviation [SD] 5.73). The prevalence of placental malaria was [4.4% (16/366) 95% CI (2.5 to 7.0)]. Of these, only 7/16 were positive on microscopy, with 2/7 having moderate parasitemia and 5/7 having mild parasitaemia. Women aged less than 20 years [AOR 3.48, 95% CI (1.13 to 10.72)], and those not taking iron supplements during pregnancy [AOR = 3.55, 95% CI (1.02 to 12.31)] were associated with an increased likelihood of having placental malaria.</p><p><strong>Conclusion: </strong>The prevalence of placental malaria was low in this setting. This may have reflected the low malaria transmission rates following intensive indoor residual spraying. Placental malaria infection was associated with younger age and not taking iron supplements during pregnancy. Public health measures need to scale up and emphasise adherence to malaria preventive measures during pregnancy especially among teenage mothers.</p>","PeriodicalId":18317,"journal":{"name":"Malaria Journal","volume":"23 1","pages":"360"},"PeriodicalIF":2.4000,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11603908/pdf/","citationCount":"0","resultStr":"{\"title\":\"Prevalence and factors associated with placental malaria in Lira District, Northern Uganda: a cross-sectional study.\",\"authors\":\"Joshua Epuitai, Grace Ndeezi, Rose Chalo Nabirye, Lydia Kabiri, David Mukunya, Josephine Tumuhamye, Faith Oguttu, James K Tumwine\",\"doi\":\"10.1186/s12936-024-05187-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Malaria has a stable perennial transmission across Uganda. Placental malaria is associated with adverse maternal, fetal, and neonatal outcomes. The factors associated with placental malaria are poorly understood in the study setting. The aim of the study was to assess the prevalence of placental malaria and to determine its associated factors among parturient women in Lira District, Uganda.</p><p><strong>Methods: </strong>This was a cross-sectional study among 366 pregnant women who delivered at Lira Regional Referral Hospital. Data were collected from December 2018 to February 2019 using an interviewer-administered questionnaire. The variables were socio-demographic, obstetric characteristics, and malaria preventive practices. Standard Diagnostic Bioline Rapid Diagnostic Tests were used to detect placental malaria present in placental blood. Microscopy was used to quantify the grade of placental malaria parasitaemia. Logistic regression was used to assess factors associated with placental malaria.</p><p><strong>Results: </strong>The mean age of the participants was 25.34 years (standard deviation [SD] 5.73). The prevalence of placental malaria was [4.4% (16/366) 95% CI (2.5 to 7.0)]. Of these, only 7/16 were positive on microscopy, with 2/7 having moderate parasitemia and 5/7 having mild parasitaemia. Women aged less than 20 years [AOR 3.48, 95% CI (1.13 to 10.72)], and those not taking iron supplements during pregnancy [AOR = 3.55, 95% CI (1.02 to 12.31)] were associated with an increased likelihood of having placental malaria.</p><p><strong>Conclusion: </strong>The prevalence of placental malaria was low in this setting. This may have reflected the low malaria transmission rates following intensive indoor residual spraying. Placental malaria infection was associated with younger age and not taking iron supplements during pregnancy. Public health measures need to scale up and emphasise adherence to malaria preventive measures during pregnancy especially among teenage mothers.</p>\",\"PeriodicalId\":18317,\"journal\":{\"name\":\"Malaria Journal\",\"volume\":\"23 1\",\"pages\":\"360\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2024-11-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11603908/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Malaria Journal\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s12936-024-05187-4\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Malaria Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12936-024-05187-4","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0

摘要

背景疟疾常年在乌干达各地稳定传播。胎盘疟疾与产妇、胎儿和新生儿的不良后果有关。在研究环境中,人们对与胎盘疟疾相关的因素知之甚少。本研究的目的是评估乌干达利拉区产妇的胎盘疟疾发病率,并确定其相关因素:这是一项横断面研究,对象是在利拉地区转诊医院分娩的 366 名孕妇。数据收集时间为 2018 年 12 月至 2019 年 2 月,采用访谈员发放的调查问卷。变量包括社会人口学、产科特征和疟疾预防做法。使用标准诊断Bioline快速诊断测试检测胎盘血液中的胎盘疟疾。显微镜检查用于量化胎盘疟疾寄生虫血症的等级。采用逻辑回归法评估与胎盘疟疾相关的因素:参与者的平均年龄为 25.34 岁(标准差 [SD] 5.73)。胎盘疟疾发病率为[4.4% (16/366) 95% CI (2.5 to 7.0)]。其中,仅有 7/16 例显微镜检查呈阳性,2/7 例为中度寄生虫血症,5/7 例为轻度寄生虫血症。年龄小于 20 岁的妇女[AOR 3.48,95% CI (1.13 至 10.72)]和孕期未服用铁补充剂的妇女[AOR = 3.55,95% CI (1.02 至 12.31)]患胎盘疟疾的可能性增加:结论:在这种情况下,胎盘疟疾的发病率较低。结论:在这一环境中,胎盘疟疾的发病率较低,这可能反映了强化室内滞留喷洒后疟疾的低传播率。胎盘疟疾感染与年龄较小及怀孕期间未服用铁补充剂有关。需要加强公共卫生措施,并强调在怀孕期间,尤其是在少女母亲中坚持采取疟疾预防措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence and factors associated with placental malaria in Lira District, Northern Uganda: a cross-sectional study.

Background: Malaria has a stable perennial transmission across Uganda. Placental malaria is associated with adverse maternal, fetal, and neonatal outcomes. The factors associated with placental malaria are poorly understood in the study setting. The aim of the study was to assess the prevalence of placental malaria and to determine its associated factors among parturient women in Lira District, Uganda.

Methods: This was a cross-sectional study among 366 pregnant women who delivered at Lira Regional Referral Hospital. Data were collected from December 2018 to February 2019 using an interviewer-administered questionnaire. The variables were socio-demographic, obstetric characteristics, and malaria preventive practices. Standard Diagnostic Bioline Rapid Diagnostic Tests were used to detect placental malaria present in placental blood. Microscopy was used to quantify the grade of placental malaria parasitaemia. Logistic regression was used to assess factors associated with placental malaria.

Results: The mean age of the participants was 25.34 years (standard deviation [SD] 5.73). The prevalence of placental malaria was [4.4% (16/366) 95% CI (2.5 to 7.0)]. Of these, only 7/16 were positive on microscopy, with 2/7 having moderate parasitemia and 5/7 having mild parasitaemia. Women aged less than 20 years [AOR 3.48, 95% CI (1.13 to 10.72)], and those not taking iron supplements during pregnancy [AOR = 3.55, 95% CI (1.02 to 12.31)] were associated with an increased likelihood of having placental malaria.

Conclusion: The prevalence of placental malaria was low in this setting. This may have reflected the low malaria transmission rates following intensive indoor residual spraying. Placental malaria infection was associated with younger age and not taking iron supplements during pregnancy. Public health measures need to scale up and emphasise adherence to malaria preventive measures during pregnancy especially among teenage mothers.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Malaria Journal
Malaria Journal 医学-寄生虫学
CiteScore
5.10
自引率
23.30%
发文量
334
审稿时长
2-4 weeks
期刊介绍: Malaria Journal is aimed at the scientific community interested in malaria in its broadest sense. It is the only journal that publishes exclusively articles on malaria and, as such, it aims to bring together knowledge from the different specialities involved in this very broad discipline, from the bench to the bedside and to the field.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信