{"title":"畜禽生产中抗菌剂使用方法及其对人类和动物健康的影响综述。","authors":"Md Ariful Islam, Palash Bose, Md Zaminur Rahman, Muhammad Muktaruzzaman, Papia Sultana, Tanvir Ahamed, Mst Minara Khatun","doi":"10.5455/javar.2024.k817","DOIUrl":null,"url":null,"abstract":"<p><p>Antimicrobials are employed in the control of contagious illnesses in humans and animals and are also utilized as growth enhancers in livestock and poultry. Improper application of antibiotics results in the development of multi-drug-resistant (MDR) bacteria, such as methicillin-resistant <i>Staphylococcus aureus</i> (MRSA), vancomycin-resistant <i>S. aureus</i> (VRSA), colistin-resistant, extended-spectrum beta-lactamase (ESBL)-producing <i>E. coli,</i> and fluoroquinolone-resistant <i>Salmonella</i>. Transmission of MDR bacteria happens among animals, from human to animal, and vice versa, resulting in treatment failure, increased treatment cost, and high morality. In this article, we analyzed the recent publications of the current antimicrobial application practices in livestock and poultry farms and the development of antimicrobial resistant (AMR) bacteria in livestock and poultry and its adverse effects on human and animal health using PubMed, Google Scholar, and Google. Citations from published articles were also analyzed. Several drug-resistant bacteria, including MRSA, VRSA, colistin-resistant strains, ESBL-producing <i>E. coli</i>, and fluoroquinolone-resistant <i>Salmonella</i>, have emerged due to heavy antibiotic application in cattle and poultry, according to the analysis. Transmission happens between people and animals as well as throughout the production chain, which raises the chance of failure of antibiotic therapy and fatality. To stop the proliferation of drug-resistant bacteria, it is important to ensure the proper use of antibiotics in livestock and poultry. Especially in developing nations, strict control and implementation of antimicrobial rules are necessary. To successfully address antimicrobial resistance and lessen dependency on antibiotics, alternative disease management strategies in livestock and poultry must be developed.</p>","PeriodicalId":14892,"journal":{"name":"Journal of Advanced Veterinary and Animal Research","volume":"11 3","pages":"675-685"},"PeriodicalIF":1.5000,"publicationDate":"2024-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11590583/pdf/","citationCount":"0","resultStr":"{\"title\":\"A review of antimicrobial usage practice in livestock and poultry production and its consequences on human and animal health.\",\"authors\":\"Md Ariful Islam, Palash Bose, Md Zaminur Rahman, Muhammad Muktaruzzaman, Papia Sultana, Tanvir Ahamed, Mst Minara Khatun\",\"doi\":\"10.5455/javar.2024.k817\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Antimicrobials are employed in the control of contagious illnesses in humans and animals and are also utilized as growth enhancers in livestock and poultry. Improper application of antibiotics results in the development of multi-drug-resistant (MDR) bacteria, such as methicillin-resistant <i>Staphylococcus aureus</i> (MRSA), vancomycin-resistant <i>S. aureus</i> (VRSA), colistin-resistant, extended-spectrum beta-lactamase (ESBL)-producing <i>E. coli,</i> and fluoroquinolone-resistant <i>Salmonella</i>. Transmission of MDR bacteria happens among animals, from human to animal, and vice versa, resulting in treatment failure, increased treatment cost, and high morality. In this article, we analyzed the recent publications of the current antimicrobial application practices in livestock and poultry farms and the development of antimicrobial resistant (AMR) bacteria in livestock and poultry and its adverse effects on human and animal health using PubMed, Google Scholar, and Google. Citations from published articles were also analyzed. Several drug-resistant bacteria, including MRSA, VRSA, colistin-resistant strains, ESBL-producing <i>E. coli</i>, and fluoroquinolone-resistant <i>Salmonella</i>, have emerged due to heavy antibiotic application in cattle and poultry, according to the analysis. Transmission happens between people and animals as well as throughout the production chain, which raises the chance of failure of antibiotic therapy and fatality. To stop the proliferation of drug-resistant bacteria, it is important to ensure the proper use of antibiotics in livestock and poultry. Especially in developing nations, strict control and implementation of antimicrobial rules are necessary. To successfully address antimicrobial resistance and lessen dependency on antibiotics, alternative disease management strategies in livestock and poultry must be developed.</p>\",\"PeriodicalId\":14892,\"journal\":{\"name\":\"Journal of Advanced Veterinary and Animal Research\",\"volume\":\"11 3\",\"pages\":\"675-685\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2024-09-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11590583/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Advanced Veterinary and Animal Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5455/javar.2024.k817\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/9/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"AGRICULTURE, DAIRY & ANIMAL SCIENCE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Advanced Veterinary and Animal Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5455/javar.2024.k817","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"AGRICULTURE, DAIRY & ANIMAL SCIENCE","Score":null,"Total":0}
引用次数: 0
摘要
抗菌素被用于控制人类和动物的传染性疾病,也被用作家畜和家禽的生长促进剂。抗生素的不当使用会导致耐多药(MDR)细菌的产生,如耐甲氧西林金黄色葡萄球菌(MRSA)、耐万古霉素金黄色葡萄球菌(VRSA)、耐大肠菌素、产广谱β-内酰胺酶(ESBL)的大肠杆菌和耐氟喹诺酮沙门氏菌。MDR 细菌在动物之间、人与动物之间以及动物与动物之间传播,导致治疗失败、治疗成本增加和高死亡率。在本文中,我们利用 PubMed、Google Scholar 和 Google 分析了近期发表的有关当前畜禽养殖场抗菌药应用实践、畜禽抗菌药耐药(AMR)细菌的发展及其对人类和动物健康的不利影响的文章。此外,还分析了已发表文章的引用情况。分析显示,由于在牛和家禽中大量使用抗生素,已经出现了多种耐药细菌,包括 MRSA、VRSA、耐大肠菌素菌株、产 ESBL 大肠杆菌和耐氟喹诺酮沙门氏菌。人与动物之间以及整个生产链中都会发生传播,这增加了抗生素治疗失败和死亡的几率。为了阻止耐药菌的扩散,必须确保在牲畜和家禽中正确使用抗生素。特别是在发展中国家,必须严格控制和执行抗菌规则。要成功解决抗菌素耐药性问题并减少对抗菌素的依赖,就必须制定替代性的畜禽疾病管理策略。
A review of antimicrobial usage practice in livestock and poultry production and its consequences on human and animal health.
Antimicrobials are employed in the control of contagious illnesses in humans and animals and are also utilized as growth enhancers in livestock and poultry. Improper application of antibiotics results in the development of multi-drug-resistant (MDR) bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant S. aureus (VRSA), colistin-resistant, extended-spectrum beta-lactamase (ESBL)-producing E. coli, and fluoroquinolone-resistant Salmonella. Transmission of MDR bacteria happens among animals, from human to animal, and vice versa, resulting in treatment failure, increased treatment cost, and high morality. In this article, we analyzed the recent publications of the current antimicrobial application practices in livestock and poultry farms and the development of antimicrobial resistant (AMR) bacteria in livestock and poultry and its adverse effects on human and animal health using PubMed, Google Scholar, and Google. Citations from published articles were also analyzed. Several drug-resistant bacteria, including MRSA, VRSA, colistin-resistant strains, ESBL-producing E. coli, and fluoroquinolone-resistant Salmonella, have emerged due to heavy antibiotic application in cattle and poultry, according to the analysis. Transmission happens between people and animals as well as throughout the production chain, which raises the chance of failure of antibiotic therapy and fatality. To stop the proliferation of drug-resistant bacteria, it is important to ensure the proper use of antibiotics in livestock and poultry. Especially in developing nations, strict control and implementation of antimicrobial rules are necessary. To successfully address antimicrobial resistance and lessen dependency on antibiotics, alternative disease management strategies in livestock and poultry must be developed.