药物护理对心力衰竭再住院的影响:随机试验。

IF 1.6 4区 医学 Q3 PHARMACOLOGY & PHARMACY
Beatriz Montero-Llorente, Covadonga Pérez Menéndez-Conde, Eduardo González Ferrer, Genoveva Teresa López Castellanos, Luis Miguel Bedoya Del Olmo, Teresa Bermejo Vicedo
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引用次数: 0

摘要

目的评估药物治疗对出院后30天因心力衰竭再次入院和到急诊就诊人数的影响,该方案基于整个治疗过程中的持续药物治疗,并评估对照组和干预组在出院后90天的差异(再次入院和到急诊就诊人数、从出院到再次入院或到急诊就诊的时间):在西班牙的一家三甲医院开展了一项单中心实验性纵向前瞻性开放式平行组研究,采用平衡随机分配(1:1)。在2019年3月至2021年11月期间,招募了被诊断为原发性或失代偿性心力衰竭并在心脏病学服务处或心力衰竭和血管风险科住院的患者,并采用随机分组模式将其随机分配到对照组(标准护理)或干预组(持续护理模式)。我们记录了流行病学、临床和药理学数据。我们使用平均差和学生 t 检验来衡量相关性。结果:共纳入 296 名患者(150 名随机分配到对照组,146 名分配到干预组)。结果显示,对照组和干预组在出院后 30 天内的再入院次数和到急诊科就诊次数上没有明显差异(P=0.092),但在 90 天内出现了统计学上的显著差异(P=0.043)。干预组患者首次到急诊科就诊或再次入院的天数更长(p=0.021):结论:药剂师在患者出院后 30 天内的持续护理和随访对心衰患者的再入院率和急诊就诊率没有影响,但在出院后 90 天内则有积极影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of pharmaceutical care on hospital readmissions for heart failure: a randomised trial.

Objectives: To evaluate the impact of pharmaceutical care on the number of readmissions and visits to the emergency department due to heart failure 30 days after hospital discharge, based on a programme of continuous pharmaceutical care throughout the care process, and to assess the differences between the control and intervention groups at 90 days after discharge (number of readmissions and visits to the emergency department, time from discharge to new readmission or visit to the emergency department).

Methods: A single-centre experimental longitudinal prospective open and parallel-group study with balanced randomisation (1:1) was carried out in a tertiary hospital in Spain. Patients with a diagnosis of primary or decompensated heart failure admitted to the Cardiology Service or the Heart Failure and Vascular Risk Unit were recruited between March 2019 and November 2021 and randomly assigned, using a randomised block model, to the control (standard care) or intervention (continuing care model) groups. Epidemiological, clinical and pharmacology data were recorded. As a measure of association, we used the mean difference and the Student's t-test. A p value of <0.05 was considered significant.

Results: 296 patients were included (150 randomised to the control group, 146 to the intervention group). The results showed no significant differences between the control and intervention groups in the number of readmissions and visits to the emergency department during the 30 days after discharge (p=0.092), but a statistically significant difference was seen at 90 days (p=0.043). The number of days until the first visit to the emergency department or readmission was higher in the intervention group (p=0.021).

Conclusions: Continuous care and follow-up by the pharmacist 30 days after discharge has a neutral impact on hospital readmissions and visits to the emergency department of patients with heart failure, but it is positive in the 90 days following discharge.

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来源期刊
CiteScore
3.40
自引率
5.90%
发文量
104
审稿时长
6-12 weeks
期刊介绍: European Journal of Hospital Pharmacy (EJHP) offers a high quality, peer-reviewed platform for the publication of practical and innovative research which aims to strengthen the profile and professional status of hospital pharmacists. EJHP is committed to being the leading journal on all aspects of hospital pharmacy, thereby advancing the science, practice and profession of hospital pharmacy. The journal aims to become a major source for education and inspiration to improve practice and the standard of patient care in hospitals and related institutions worldwide. EJHP is the only official journal of the European Association of Hospital Pharmacists.
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