腹部结核性肿块病变引起的阻塞性黄疸。

IF 0.8 Q4 GASTROENTEROLOGY & HEPATOLOGY
Wilson Jing Peng Liu, Michael Yulong Wu, Matthew Zaborowski, Eugene Ng
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引用次数: 0

摘要

结核病是一种全球性流行感染,通常表现为影响呼吸系统的症状。腹部结核是一种不常见的表现,仅占全球结核病例的 5%,可表现为一系列模糊症状,与其他胆道和胰腺病变相似。我们报告了一例因腹腔结核继发黄疸和胆道梗阻的 36 岁女性病例。计算机断层扫描和磁共振胆胰造影显示,腹膜后肿块与胰头和十二指肠相邻,伴有胆总管扩张。内镜超声显示十二指肠内有一个溃疡性肿块,并进行了活检。组织学检查发现了坏死性肉芽肿,活检组织在结核聚合酶链反应检测中呈阳性。因此,确诊为腹腔外肺结核。患者开始接受为期 6 个月的利福平、异烟肼、吡嗪酰胺和乙胺丁醇治疗,并对药物治疗产生了完全反应。腹部结核病可能很难诊断,但对于曾在流行地区旅行或居住过并伴有胃肠道症状的患者来说,腹部结核病仍是一个重要的鉴别依据。及时诊断和治疗可避免腹部结核引起胆道梗阻的患者接受不必要的手术、出现并发症和死亡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Obstructive jaundice caused by an abdominal tuberculous mass lesion.

Tuberculosis is a global epidemic infection that typically presents with symptoms affecting the respiratory system. Abdominal tuberculosis is an uncommon manifestation, occurring in only 5% of tuberculosis cases globally and can present with a broad range of vague symptoms that mimic other biliary and pancreatic pathologies. We report a case of a 36-year-old woman presenting with jaundice and biliary obstruction secondary to abdominal tuberculosis. Computed tomography and magnetic resonance cholangiopancreatography revealed a loculated retroperitoneal mass abutting the pancreatic head and duodenum with associated common bile duct dilatation. Endoscopic ultrasound demonstrated an ulcerated mass in the duodenum which was biopsied. Necrotising granulomas were identified on histology and the biopsied tissue was positive on tuberculosis polymerase chain reaction testing. Thus, extrapulmonary abdominal tuberculosis was diagnosed. The patient was commenced on a 6-month course of rifampicin, isoniazid, pyrazinamide and ethambutol treatment and demonstrated complete response to medical therapy. Abdominal tuberculosis can be difficult to diagnose but should remain an important differential to be considered for patients with previous travel or residence in endemic areas presenting with gastrointestinal symptoms. Prompt diagnosis and treatment can prevent unnecessary procedures, complications and death in patients with biliary obstruction caused by abdominal tuberculosis.

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来源期刊
Clinical Journal of Gastroenterology
Clinical Journal of Gastroenterology GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
2.00
自引率
0.00%
发文量
182
期刊介绍: The journal publishes Case Reports and Clinical Reviews on all aspects of the digestive tract, liver, biliary tract, and pancreas. Critical Case Reports that show originality or have educational implications for diagnosis and treatment are especially encouraged for submission. Personal reviews of clinical gastroenterology are also welcomed. The journal aims for quick publication of such critical Case Reports and Clinical Reviews.
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