抗生素推动溶瘤病毒疗法的发展

IF 26.8 1区医学 Q1 ENGINEERING, BIOMEDICAL

Nature Biomedical Engineering Pub Date : 2024-11-28 DOI:10.1038/s41551-024-01269-5

Himanshu Soni, E. Antonio Chiocca, Joshua D. Bernstock

引用次数: 0

摘要

表达免疫调节细胞因子转基因的肿瘤溶解病毒可利用病毒对某些抗生素的敏感性进行高通量生产。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Antibiotic-driven boosting of oncolytic virotherapy

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Antibiotic-driven boosting of oncolytic virotherapy

Oncolytic viruses expressing transgenes for immunomodulatory cytokines can be produced at high throughput by exploiting the preferential susceptibility of the viruses to certain antibiotics.

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来源期刊

Nature Biomedical Engineering Medicine-Medicine (miscellaneous)

CiteScore

45.30

自引率

1.10%

发文量

138

期刊介绍： Nature Biomedical Engineering is an online-only monthly journal that was launched in January 2017. It aims to publish original research, reviews, and commentary focusing on applied biomedicine and health technology. The journal targets a diverse audience, including life scientists who are involved in developing experimental or computational systems and methods to enhance our understanding of human physiology. It also covers biomedical researchers and engineers who are engaged in designing or optimizing therapies, assays, devices, or procedures for diagnosing or treating diseases. Additionally, clinicians, who make use of research outputs to evaluate patient health or administer therapy in various clinical settings and healthcare contexts, are also part of the target audience.