Andreina Carbone, Emanuele Monda, Francesco Ferrara, Monica Franzese, Roberta Bottino, Valentina Russo, Chiara Cirillo, Salvatore Rega, Antonio Cittadini, Antonio Pelliccia, Giuseppe Limongelli, Eduardo Bossone
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Data were aggregated using a random effects model for estimating the pooled risk ratio and mean difference.</p><p><strong>Results: </strong>Absolute aortic diameters at the sinus of Valsalva (AoSV) were higher in overall elite athletes compared to non-athlete healthy controls (mean difference [MD] 1.69 [95% CI 1.01-2.37] mm; p <0.001) and if stratified to sex. This difference was maintained if AoSV was indexed to height (AoSV/h) (MD 0.04 [95% CI -0.00-0.08] mm/m; ES 2.18 [95% CI 1.10-3.26]; p<0.001). The analysis of AoSV/h according to sex was not performed for the paucity of studies. However, when indexed to body surface area (AoSV/BSA), no differences were found between the two groups (MD 0.04 [95% CI -0.25-0.34] mm/m2; p = 0.880), also according to sex. Above findings were not influenced by age.</p><p><strong>Conclusions: </strong>Absolute AoSV was mildly larger in athletes compared to non-athlete healthy controls, even when indexed to height. However, no differences were evident when indexed by BSA, irrespective of sex, type of sport and age. Therefore, assessment of the aortic size in elite athletes should consider the proper normalization in order to avoid misdiagnosis of aortopathies.</p><p><strong>Prospero registry id: </strong>CRD42024561255.</p>","PeriodicalId":12051,"journal":{"name":"European journal of preventive cardiology","volume":" ","pages":""},"PeriodicalIF":8.4000,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Aortic Dimension in Elite Athletes: Updated Systematic Review and Meta-Analysis.\",\"authors\":\"Andreina Carbone, Emanuele Monda, Francesco Ferrara, Monica Franzese, Roberta Bottino, Valentina Russo, Chiara Cirillo, Salvatore Rega, Antonio Cittadini, Antonio Pelliccia, Giuseppe Limongelli, Eduardo Bossone\",\"doi\":\"10.1093/eurjpc/zwae385\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aims: </strong>To assess the presence and the extent of an \\\"aortic remodeling\\\" in elite athletes.</p><p><strong>Methods: </strong>A systematic review and meta-analysis of literature were conducted for studies (1981-2024) reporting echocardiographic aortic diameters of elite athletes compared to non-athlete healthy controls. 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引用次数: 0
摘要
目的：评估精英运动员是否存在 "主动脉重塑 "及其程度：对报道精英运动员与非运动员健康对照组主动脉直径超声心动图对比的研究（1981-2024 年）进行了系统回顾和文献荟萃分析。在检索到的5494项研究中，有21项（9464名精英运动员与2637名非运动员对照组）符合所有资格标准。采用随机效应模型对数据进行汇总，以估算汇总风险比和平均差异：结果：与非运动员健康对照组相比，精英运动员在瓦尔萨尔瓦窦处的主动脉绝对直径（AoSV）更高（平均差[MD] 1.69 [95% CI 1.01-2.37] mm; p 结论：精英运动员在瓦尔萨尔瓦窦处的主动脉绝对直径略高于非运动员健康对照组（平均差[MD] 1.69 [95% CI 1.01-2.37] mm; p）：与非运动员健康对照组相比，即使以身高为指数，运动员的绝对AoSV也略大于非运动员健康对照组。然而，无论性别、运动类型和年龄如何，以 BSA 为指标时均无明显差异。因此，在评估精英运动员的主动脉尺寸时应考虑适当的正常化，以避免误诊主动脉疾病：CRD42024561255。
Aortic Dimension in Elite Athletes: Updated Systematic Review and Meta-Analysis.
Aims: To assess the presence and the extent of an "aortic remodeling" in elite athletes.
Methods: A systematic review and meta-analysis of literature were conducted for studies (1981-2024) reporting echocardiographic aortic diameters of elite athletes compared to non-athlete healthy controls. Among the 5,494 studies retrieved, 21 (9,464 elite athletes vs. 2,637 non-athlete controls) fulfilled all eligibility criteria. Data were aggregated using a random effects model for estimating the pooled risk ratio and mean difference.
Results: Absolute aortic diameters at the sinus of Valsalva (AoSV) were higher in overall elite athletes compared to non-athlete healthy controls (mean difference [MD] 1.69 [95% CI 1.01-2.37] mm; p <0.001) and if stratified to sex. This difference was maintained if AoSV was indexed to height (AoSV/h) (MD 0.04 [95% CI -0.00-0.08] mm/m; ES 2.18 [95% CI 1.10-3.26]; p<0.001). The analysis of AoSV/h according to sex was not performed for the paucity of studies. However, when indexed to body surface area (AoSV/BSA), no differences were found between the two groups (MD 0.04 [95% CI -0.25-0.34] mm/m2; p = 0.880), also according to sex. Above findings were not influenced by age.
Conclusions: Absolute AoSV was mildly larger in athletes compared to non-athlete healthy controls, even when indexed to height. However, no differences were evident when indexed by BSA, irrespective of sex, type of sport and age. Therefore, assessment of the aortic size in elite athletes should consider the proper normalization in order to avoid misdiagnosis of aortopathies.
期刊介绍：
European Journal of Preventive Cardiology (EJPC) is an official journal of the European Society of Cardiology (ESC) and the European Association of Preventive Cardiology (EAPC). The journal covers a wide range of scientific, clinical, and public health disciplines related to cardiovascular disease prevention, risk factor management, cardiovascular rehabilitation, population science and public health, and exercise physiology. The categories covered by the journal include classical risk factors and treatment, lifestyle risk factors, non-modifiable cardiovascular risk factors, cardiovascular conditions, concomitant pathological conditions, sport cardiology, diagnostic tests, care settings, epidemiology, pharmacology and pharmacotherapy, machine learning, and artificial intelligence.
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