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引用次数: 0
摘要
预防食物过敏(FA)的策略是及早引入固体过敏原,尽管建议有所改变,但鉴于食物过敏的发病率仍在上升,这一策略似乎还不够。通过涂抹润肤剂来恢复皮肤屏障的补充策略已经研究了数年。评估这种策略有效性的临床研究提供了相互矛盾的结果,但研究方案差异很大:有些润肤剂实际上对皮肤屏障有害,而涂抹的频率或面积可能不足以对皮肤屏障产生积极影响。这些研究表明,使用酸性 pH 值(约 5.5)的润肤剂(最好是神经酰胺类)将有利于 FA 的一级预防。此外,避免使用含有过敏原(包括食品衍生物)的化妆品也很重要。这些简单的建议已经可以由初级保健医生提供。
Stratégies ciblant la peau en prévention des allergies alimentaires
The strategy for preventing food allergies (FA) based on the early introduction of solid allergens appears insufficient, given the increasing incidence of FA despite changes in recommendations. The complementary strategy aimed at restoring the skin barrier by applying emollients has been studied for several years. Clinical studies evaluating the effectiveness of such strategy provided conflicting results, but the study protocols are highly heterogeneous: some emollients used are actually harmful to the skin barrier, while the frequency or area of application may be insufficient to have a positive impact on the skin barrier. These studies suggest that the application of an emollient with an acidic pH (around 5.5) and ideally ceramide-based would be beneficial in the primary prevention of FA. Additionally, it is important to avoid cosmetic products containing allergens, including food derivatives. These few simple advices can already be provided by primary care physicians.
期刊介绍:
La Revue Française d''Allergologie : un véritable forum pour faire connaître des travaux originaux et permettre la diffusion de l''information auprès de toutes les spécialités concernées par les pathologies allergiques. La Revue Française d''Allergologie (8 numéros par an) est au carrefour de nombreuses spécialités - dermatologie, pédiatrie, ORL, pneumologie, ophtalmologie, médecine interne - qui, toutes, ont à traiter des maladies allergiques. Les symptômes des allergies fondés sur des mécanismes communs sont le plus souvent associés et se succèdent chez un même patient. En forte progression depuis 20 ans, les maladies allergiques sont dans l''attente de perfectionnements et d''avancées thérapeutiques qui permettront aux nombreux patients qui en sont atteints de mieux vivre avec leurs allergies. La Revue Française d''Allergologie se veut donc un véritable forum de discussions et d''échanges entre tous les spécialistes confrontés aux pathologies