Delainey L. Wescott , Brant P. Hasler , Jill E. Foust , Kathryn A. Roecklein
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引用次数: 0
摘要
旨在调整昼夜节律系统的时间治疗干预可以改善抑郁症。本系统综述评估了昼夜节律调整作为抗抑郁机制的现有证据。我们使用 PubMed、EMBASE、Cochrane Central Register of Controlled Trials (Wiley)、Europe PMC 和 PsycINFO 对在抑郁症和/或睡眠/昼夜节律延迟样本中实施昼夜节律治疗干预的研究进行了全面检索。唐斯和布莱克核对表用于评估研究质量。共纳入 58 项研究,其中 23 项研究报告了昼夜节律调整与抑郁之间的关系。在纳入基线延迟和抑郁程度升高的参与者的研究中,昼夜节律调整与抑郁程度的改善有关。要进一步阐明昼夜节律调整作为一种抗抑郁机制,需要进行测量昼夜节律相位标记的随机临床试验。
Circadian realignment and depressed mood: A systematic review
Chronotherapeutic interventions aimed at realigning the circadian system can improve depression. This systematic review evaluated the current evidence for circadian realignment as an antidepressant mechanism. A comprehensive search was conducted in studies that implemented a chronotherapeutic intervention in samples with depression and/or delayed sleep/circadian timing using PubMed, EMBASE, Cochrane Central Register of Controlled Trials (Wiley), Europe PMC, and PsycINFO. The Downs and Black checklist was used to evaluate study quality. There were 58 studies included, of which 23 studies reported the association between realignment and depression. Circadian realignment was associated with improved depression in studies that included participants with baseline delays and elevated depression. Randomized clinical trials measuring circadian phase markers are needed to further elucidate circadian realignment as an antidepressant mechanism.
期刊介绍:
Sleep Medicine Reviews offers global coverage of sleep disorders, exploring their origins, diagnosis, treatment, and implications for related conditions at both individual and public health levels.
Articles comprehensively review clinical information from peer-reviewed journals across various disciplines in sleep medicine, encompassing pulmonology, psychiatry, psychology, physiology, otolaryngology, pediatrics, geriatrics, cardiology, dentistry, nursing, neurology, and general medicine.
The journal features narrative reviews, systematic reviews, and editorials addressing areas of controversy, debate, and future research within the field.