彻底改变 X 射线成像:利用级联工程方法实现超低剂量检测的飞跃

IF 12.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Xin Song, Xinyuan Zhang, Tengyue He, Jiayi Wang, Hongwei Zhu, Renqian Zhou, Taimoor Ahmad, Osman M. Bakr and Omar F. Mohammed*, 
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引用次数: 0

摘要

X 射线检测技术在医疗成像和安全检查等多个领域都非常重要。然而,暴露于大剂量的 X 射线会对健康造成相当大的威胁。因此,在不影响检测效率的前提下减少辐射剂量至关重要。为了解决这个问题,我们提出了一种创新的级联工程方法,利用两个相互连接的单晶器件来减轻暗电流并提高探测极限。我们利用实验室生长的溴化甲基铵铅 (MAPbBr3) 包晶石单晶,设计出了能显著降低检测阈值并提高信噪比 (SNR) 的器件。使用级联方法,检测阈值从传统方法的 590 nGy-s-1 降至 100 nGy-s-1,超过了 MAPbBr3 器件在几乎相同条件下达到的 500 nGy-s-1 的最新记录。与传统设备相比,暗电流减半,空间分辨率从 5.6 lp-mm-1 提高到 8.5 lp-mm-1。成像试验证实,在低剂量的情况下,分辨率和有效性都得到了提高,这凸显了这种方法在医疗诊断方面的潜力,因为医疗诊断优先考虑的是在不影响图像质量的情况下减少辐射照射。碲化镉晶体对不同电气环境和晶体类型的适应性凸显了这一方法的开创性,表明它有潜力广泛应用于低剂量泄漏监测和商业 X 射线设备。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Revolutionizing X-ray Imaging: A Leap toward Ultra-Low-Dose Detection with a Cascade-Engineered Approach

X-ray detection technology is essential in various fields, including medical imaging and security checks. However, exposure to large doses of X-rays poses considerable health risks. Therefore, it is crucial to reduce the radiation dosage without compromising detection efficiency. To address this concern, we propose an innovative cascade-engineered approach that uses two interconnected single-crystal devices to mitigate dark current and enhance the detection limit. Using laboratory-grown methylammonium lead bromide (MAPbBr3) perovskite single crystals, we engineered devices that significantly reduced detection thresholds and improved signal-to-noise ratios (SNRs). The detection threshold dropped from 590 nGy·s–1 with the conventional method to 100 nGy·s–1 using the cascade approach, surpassing the most recent record of 500 nGy·s–1 achieved for MAPbBr3 devices under nearly identical conditions. The dark current was halved compared to that of conventional devices, and spatial resolution improved from 5.6 to 8.5 lp·mm–1. Imaging trials confirmed improved resolution and effectiveness at low doses, highlighting the approach’s potential for medical diagnostics that prioritizes reducing radiation exposure without compromising image quality. The groundbreaking nature of this approach is highlighted by its adaptability across diverse electrical environments and crystal types, as evident in CdTe crystals, indicating its potential for widespread utilization in low-dose leakage monitoring and commercial X-ray devices.

This study explores a novel cascade-engineering device designed for low-dose X-ray detection.

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来源期刊
ACS Central Science
ACS Central Science Chemical Engineering-General Chemical Engineering
CiteScore
25.50
自引率
0.50%
发文量
194
审稿时长
10 weeks
期刊介绍: ACS Central Science publishes significant primary reports on research in chemistry and allied fields where chemical approaches are pivotal. As the first fully open-access journal by the American Chemical Society, it covers compelling and important contributions to the broad chemistry and scientific community. "Central science," a term popularized nearly 40 years ago, emphasizes chemistry's central role in connecting physical and life sciences, and fundamental sciences with applied disciplines like medicine and engineering. The journal focuses on exceptional quality articles, addressing advances in fundamental chemistry and interdisciplinary research.
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