高强度有氧训练对代谢综合征的临床和生理影响:了解个体运动反应的差异性。

IF 3.3 3区 医学 Q1 PHYSIOLOGY
Alfonso Moreno-Cabañas, Felix Morales-Palomo, Laura Alvarez-Jimenez, Diego Mora-Gonzalez, Eva Garcia-Camacho, Belen Martinez-Mulero, Ricardo Mora-Rodriguez
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引用次数: 0

摘要

我们分析了代谢综合征(MetS)患者对有监督的高强度间歇训练(HIIT)计划的健康反应的个体间异质性。264 名超重/肥胖(56.3±7.3 岁,体重指数 32.3±4.7kg-m-2)和 MetS 患者被随机分配到标准保健非运动组(CONT 组,58 人)或标准保健加 HIIT 组(EXER 组,206 人)。HIIT 干预每周三次,每次 43 分钟。在干预前(0 周)和干预后(16 周),对两组的 MetS 成分(即 MetS z 评分)、心肺功能(VO2PEAK)、最大骑行功率(WPEAK)和体重/体型的变化进行了评估。如果 EXER 组的个体反应改善大于典型误差的两倍(>2 TE),则认为是 HIIT 的结果。TE是通过时间匹配的CONT组的干预前和干预后数据计算得出的。由于血压(45%)和腰围(48%)的降低,MetS z 评分改善超过 2TE 的参与者比例为 51%。血脂和血糖反应仅为 21% 和 16%(改善超过 2TE 的参与者)。60%的 MetS z 评分改善者的 VO2PEAK 也有所改善(r=-0.013;P=0.86),而 85% 的 MetS z 评分改善者的 WPEAK 也有所改善(r=0.151;P=0.03)。总之,医疗服务提供者可以预期,为期 16 周的 HIIT 计划将无可争议地改善约 50% 完成计划者的 MetS 状况。最后,在无法直接评估 MetS 五大因素的情况下,WPEAK 比 VO2PEAK 更能预测哪些人会改善 MetS。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical and physiological effects of high-intensity aerobic training on metabolic syndrome: understanding the individual exercise response variability.

We analyzed the interindividual heterogeneity in health responses to a supervised high-intensity interval training (HIIT) program in individuals with metabolic syndrome (MetS). Two-hundred and sixty-four adults with overweight/obesity (56.3±7.3 y, body mass index, 32.3±4.7 kg·m-2), and MetS were randomized to a standard health care non-exercise group (CONT group, N=58) or standard health care plus HIIT (EXER group, N=206). HIIT intervention was performed on a cycloergometer thrice a week (43 min·session-1). The change in MetS components (i.e., MetS z score), cardiorespiratory fitness (VO2PEAK), maximal cycling power (WPEAK), and body weight/composition was assessed in both groups before (0 weeks) and after the intervention (16 weeks). Individual responses in the EXER group were considered attributable to HIIT when the improvements were larger than twice the typical error (>2 TE). TE was calculated using pre- and post-intervention data from the time-matched CONT group. The percent of participants that improved MetS z score beyond 2TE was 51% driven by reductions in blood pressure (45%) and waist circumference (48%). Blood lipids and glucose response were only 21% and 16% (participants improving beyond 2TE). Sixty percent of individuals that improved MetS z score, also improved VO2PEAK (r=-0.013; P=0.86) while 85% of individuals improving MetS z score also improved WPEAK (r=0.151; P=0.03). In summary, health providers can expect that a 16- week HIIT program would indisputably improve MetS in approximately 50% of individuals completing the program. Lastly, WPEAK better predicts which individuals would improve MetS than VO2PEAK when the direct assessment of the five MetS factors is not feasible.

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来源期刊
CiteScore
6.00
自引率
9.10%
发文量
296
审稿时长
2-4 weeks
期刊介绍: The Journal of Applied Physiology publishes the highest quality original research and reviews that examine novel adaptive and integrative physiological mechanisms in humans and animals that advance the field. The journal encourages the submission of manuscripts that examine the acute and adaptive responses of various organs, tissues, cells and/or molecular pathways to environmental, physiological and/or pathophysiological stressors. As an applied physiology journal, topics of interest are not limited to a particular organ system. The journal, therefore, considers a wide array of integrative and translational research topics examining the mechanisms involved in disease processes and mitigation strategies, as well as the promotion of health and well-being throughout the lifespan. Priority is given to manuscripts that provide mechanistic insight deemed to exert an impact on the field.
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