肠道微生物组调控的最新进展:益生菌、益生元、合成益生菌和后益生菌在炎症性肠病预防和治疗中的作用》(Effect of Probiotics, Prebiotics, Synbiotics, and Postbiotics in Inflammatory Bowel Disease Prevention and Treatment)。

IF 2.3 3区 生物学 Q3 MICROBIOLOGY
Samira Saedi, Safoura Derakhshan, Alka Hasani, Manouchehr Khoshbaten, Vahdat Poortahmasebi, Payam Gonbari Milani, Javid Sadeghi
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引用次数: 0

摘要

人体胃肠道中含有数万亿对身体有影响的微生物。肠道微生物群组成失调是导致炎症性肠病(IBD)等慢性炎症性疾病的主要原因之一。IBD 是一项全球性的公共卫生挑战,世界上有数百万人患有这种疾病。它是一种反复发作的炎症性疾病,影响人体消化系统的不同部位。溃疡性结肠炎和克罗恩病是 IBD 的两种主要类型,临床症状相似。IBD 的发病率和严重程度不断增加,需要新的治疗方法。肠道微生物群的组成可以通过膳食补充剂来改变,如益生元和被称为益生菌的细菌补充剂。此外,还可以通过使用辅助生物制剂(无法存活的灭活细菌或其成分)和/或后生物制剂(细菌代谢产物)来改善微生物群的效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recent Advances in Gut Microbiome Modulation: Effect of Probiotics, Prebiotics, Synbiotics, and Postbiotics in Inflammatory Bowel Disease Prevention and Treatment.

The human gastrointestinal tract contains trillions of microbes that affect the body. Dysbiosis in the composition of gut microbiota is one of the leading causes of chronic inflammatory diseases such as inflammatory bowel disease (IBD). IBD is a global public health challenge and millions of people in the world are suffering from this disease. It is a recurring inflammatory disease that affects different parts of the human digestive system. Ulcerative colitis and Crohn's disease are the two main types of IBD with similar clinical symptoms. The increasing incidence and severity of IBD require new treatment methods. The composition of the gut microbiota can be modified using dietary supplements such as prebiotics and bacterial supplements called probiotics. Furthermore, the effects of the microbiome can be improved by using paraprobiotics (non-viable, inactivated bacteria or their components) and/or postbiotics (products of bacterial metabolism).

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来源期刊
Current Microbiology
Current Microbiology 生物-微生物学
CiteScore
4.80
自引率
3.80%
发文量
380
审稿时长
2.5 months
期刊介绍: Current Microbiology is a well-established journal that publishes articles in all aspects of microbial cells and the interactions between the microorganisms, their hosts and the environment. Current Microbiology publishes original research articles, short communications, reviews and letters to the editor, spanning the following areas: physiology, biochemistry, genetics, genomics, biotechnology, ecology, evolution, morphology, taxonomy, diagnostic methods, medical and clinical microbiology and immunology as applied to microorganisms.
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