{"title":"利用单色激发 X 射线荧光光谱法快速测定头发中的有毒痕量金属砷、汞、碲和铅。","authors":"Shihao Wu, Peng Zhao, Aihua Wang, Linpei Dong, Xiaojun Wu, Jifen Wang, Yunfeng Zhang","doi":"10.1007/s12011-024-04455-3","DOIUrl":null,"url":null,"abstract":"<p><p>Monochromatic excitation X-ray fluorescence (ME-XRF) spectrometry emerges as a novel technique in trace element analysis, distinguished by its simplicity, rapidity, and efficiency. Its application in forensic toxicology has grown significantly for identifying toxic trace metals in biological samples. This study further expands its utility by developing a method for the rapid determination of arsenic (As), mercury (Hg), thallium (Tl), and lead (Pb) in hair samples. Calibration curves were established using analytical reference samples, and optimal detection conditions were determined and validated. The LODs for As, Hg, Tl, and Pb were 0.03, 0.03, 0.03, and 0.05 μg g<sup>-1</sup>, respectively. Method precision was evaluated through seven parallel analyses of samples within the concentration range of 0.27 to 20.051 μg g⁻<sup>1</sup>, with relative standard deviations (RSDs) consistently below 10%. The feasibility of the ME-XRF technique for forensic toxicology analysis was validated through the analysis of authentic poisoned hair samples collected from the animal experiment.</p>","PeriodicalId":8917,"journal":{"name":"Biological Trace Element Research","volume":" ","pages":""},"PeriodicalIF":3.4000,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Rapid Determination of Toxic Trace Metals As, Hg, Tl, and Pb in Hair by Monochromatic Excitation X-ray Fluorescence Spectrometry.\",\"authors\":\"Shihao Wu, Peng Zhao, Aihua Wang, Linpei Dong, Xiaojun Wu, Jifen Wang, Yunfeng Zhang\",\"doi\":\"10.1007/s12011-024-04455-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Monochromatic excitation X-ray fluorescence (ME-XRF) spectrometry emerges as a novel technique in trace element analysis, distinguished by its simplicity, rapidity, and efficiency. Its application in forensic toxicology has grown significantly for identifying toxic trace metals in biological samples. This study further expands its utility by developing a method for the rapid determination of arsenic (As), mercury (Hg), thallium (Tl), and lead (Pb) in hair samples. Calibration curves were established using analytical reference samples, and optimal detection conditions were determined and validated. The LODs for As, Hg, Tl, and Pb were 0.03, 0.03, 0.03, and 0.05 μg g<sup>-1</sup>, respectively. Method precision was evaluated through seven parallel analyses of samples within the concentration range of 0.27 to 20.051 μg g⁻<sup>1</sup>, with relative standard deviations (RSDs) consistently below 10%. The feasibility of the ME-XRF technique for forensic toxicology analysis was validated through the analysis of authentic poisoned hair samples collected from the animal experiment.</p>\",\"PeriodicalId\":8917,\"journal\":{\"name\":\"Biological Trace Element Research\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2024-11-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biological Trace Element Research\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1007/s12011-024-04455-3\",\"RegionNum\":3,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biological Trace Element Research","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1007/s12011-024-04455-3","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
Rapid Determination of Toxic Trace Metals As, Hg, Tl, and Pb in Hair by Monochromatic Excitation X-ray Fluorescence Spectrometry.
Monochromatic excitation X-ray fluorescence (ME-XRF) spectrometry emerges as a novel technique in trace element analysis, distinguished by its simplicity, rapidity, and efficiency. Its application in forensic toxicology has grown significantly for identifying toxic trace metals in biological samples. This study further expands its utility by developing a method for the rapid determination of arsenic (As), mercury (Hg), thallium (Tl), and lead (Pb) in hair samples. Calibration curves were established using analytical reference samples, and optimal detection conditions were determined and validated. The LODs for As, Hg, Tl, and Pb were 0.03, 0.03, 0.03, and 0.05 μg g-1, respectively. Method precision was evaluated through seven parallel analyses of samples within the concentration range of 0.27 to 20.051 μg g⁻1, with relative standard deviations (RSDs) consistently below 10%. The feasibility of the ME-XRF technique for forensic toxicology analysis was validated through the analysis of authentic poisoned hair samples collected from the animal experiment.
期刊介绍：
Biological Trace Element Research provides a much-needed central forum for the emergent, interdisciplinary field of research on the biological, environmental, and biomedical roles of trace elements. Rather than confine itself to biochemistry, the journal emphasizes the integrative aspects of trace metal research in all appropriate fields, publishing human and animal nutritional studies devoted to the fundamental chemistry and biochemistry at issue as well as to the elucidation of the relevant aspects of preventive medicine, epidemiology, clinical chemistry, agriculture, endocrinology, animal science, pharmacology, microbiology, toxicology, virology, marine biology, sensory physiology, developmental biology, and related fields.
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