{"title":"单核细胞衍生细胞中的线粒体促进了多发性硬化症的组织损伤","authors":"Zi Yan Chen, Arthur Mortha","doi":"10.1038/s41577-024-01116-3","DOIUrl":null,"url":null,"abstract":"A preprint by Villar-Vesga et al. shows that monocyte-derived cells in the central nervous system produce mitochondrial reactive oxygen species to promote neuroinflammation.","PeriodicalId":19049,"journal":{"name":"Nature Reviews Immunology","volume":"25 1","pages":"3-3"},"PeriodicalIF":67.7000,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Mitochondria in monocyte-derived cells promote tissue damage in multiple sclerosis\",\"authors\":\"Zi Yan Chen, Arthur Mortha\",\"doi\":\"10.1038/s41577-024-01116-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A preprint by Villar-Vesga et al. shows that monocyte-derived cells in the central nervous system produce mitochondrial reactive oxygen species to promote neuroinflammation.\",\"PeriodicalId\":19049,\"journal\":{\"name\":\"Nature Reviews Immunology\",\"volume\":\"25 1\",\"pages\":\"3-3\"},\"PeriodicalIF\":67.7000,\"publicationDate\":\"2024-11-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature Reviews Immunology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.nature.com/articles/s41577-024-01116-3\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"IMMUNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Reviews Immunology","FirstCategoryId":"3","ListUrlMain":"https://www.nature.com/articles/s41577-024-01116-3","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
Mitochondria in monocyte-derived cells promote tissue damage in multiple sclerosis
A preprint by Villar-Vesga et al. shows that monocyte-derived cells in the central nervous system produce mitochondrial reactive oxygen species to promote neuroinflammation.
期刊介绍:
Nature Reviews Immunology is a journal that provides comprehensive coverage of all areas of immunology, including fundamental mechanisms and applied aspects. It has two international standard serial numbers (ISSN): 1474-1733 for print and 1474-1741 for online. In addition to review articles, the journal also features recent developments and new primary papers in the field, as well as reflections on influential people, papers, and events in the development of immunology. The subjects covered by Nature Reviews Immunology include allergy and asthma, autoimmunity, antigen processing and presentation, apoptosis and cell death, chemokines and chemokine receptors, cytokines and cytokine receptors, development and function of cells of the immune system, haematopoiesis, infection and immunity, immunotherapy, innate immunity, mucosal immunology and the microbiota, regulation of the immune response, signalling in the immune system, transplantation, tumour immunology and immunotherapy, and vaccine development.