成人下咽血管畸形的治疗--描述性研究

Xiufa Wu, Jing Zhang, Chunsheng Wei
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摘要

研究目的鉴于成人下咽血管异常(AHVAs)的罕见性,目前还没有系统性的研究。本研究旨在探索 AHVA 的治疗策略,并确定手术治疗的最佳时机。研究方法我们对2013年9月至2022年11月期间在我科接受博莱霉素注射或切除术治疗的AHVAs患者数据进行了回顾性分析。研究评估了疗效、影响疗效的因素、AHVAs的大小以及手术方法的选择。研究结果共有 23 名成人患者接受了 30 种不同的手术。研究显示,手术方法的选择对疗效有显著影响,其中磷酸三硫化钛钾激光、二氧化碳(CO2)激光、低温等离子体和钬激光对治疗 AHVAs 有效。与单个亚区受侵的 AHVA 相比,涉及多个亚区的 AHVA 治疗效果更差。值得注意的是,3 名患者接受了两次手术:第一次是注射博莱霉素,第二次是完全切除。结论:我们的研究结果强调了在明确划分 AHVA 的情况下,手术切除能取得更好的疗效。此外,我们建议在博莱霉素注射诱导 AHVAs 减少后选择手术切除。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Management of Adult Hypopharyngeal Vascular Anomalies-A Descriptive Study.

Objective: Given the rarity of adult hypopharyngeal vascular anomalies (AHVAs), no systematic studies are currently available. The aim of this study is to explore therapeutic strategies for AHVAs and determine the optimal timing for surgery in their treatment. Methods: We conducted a retrospective analysis of the data from patients diagnosed with AHVAs who underwent treatment using either bleomycin injection or excision methods in our department between September 2013 and November 2022. The study evaluated the curative efficacy, factors influencing efficacy, the size of AHVAs, and the selection of surgical methods. Results: A total of 23 adult patients underwent 30 distinct procedures. The study revealed that the choice of surgical methods significantly impacted therapeutic outcomes, with potassium-titanyl-phosphate laser, carbon dioxide (CO2) lasers, low-temperature plasma, and Holmium laser proving effective in treating AHVAs. The therapeutic effect was found to be worse for AHVAs involving multiple subzones compared to those with single subzone invasion. Notably, 3 patients underwent 2 surgeries: the first involved a bleomycin injection, followed by a complete surgical excision. Conclusions: The findings of our study emphasize the superior outcomes achieved through surgical excision when AHVAs are clearly delineated. Furthermore, we recommend opting for surgical excision after a reduction of AHVAs induced by bleomycin injection.

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