预测经导管二尖瓣边缘至边缘修复术后再住院的前负荷可招募卒中功关系斜率的实用性。

IF 3.1 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Circulation Journal Pub Date : 2024-11-22 DOI:10.1253/circj.CJ-24-0497

Yasushige Shingu, Jien Saito, Kiwamu Kamiya, Toshiyuki Nagai, Toshihisa Anzai, Satoru Wakasa

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引用次数: 0

摘要

背景：在功能性二尖瓣反流（FMR）患者中，经导管二尖瓣边缘到边缘修复术（TEER）的响应者仍不明确。我们研究了前负荷可招募搏出功关系的斜率（Mw；计算公式为搏出功/[EDV - k × EDV + {1 - k} × LV壁]，其中EDV为舒张末期容积，k为常数，LV壁为左室壁容积）能否预测功能性二尖瓣反流患者在TEER术后的再住院情况：使用超声心动图计算了 24 例 FMR 患者的 Mww。中位左室射血分数为 27%，中位 Mww 为 32。在498天的中位随访期内，38%的患者因心衰再次入院，在时间依赖性接收器操作特征分析中，只有Mww的曲线下面积较高：结论：Mw是预测心力衰竭患者在TEER术后再次住院的有效指标。

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Usefulness of the Slope of the Preload Recruitable Stroke Work Relationship for the Prediction of Rehospitalization After Transcatheter Mitral Edge-to-Edge Repair.

Background: Among patients with functional mitral regurgitation (FMR), responders to transcatheter mitral edge-to-edge repair (TEER) remain unclear. We investigated whether the slope of the preload recruitable stroke work relationship (M_w; calculated as stroke work / [EDV - k × EDV + {1 - k} × LV wall], where EDV is end-diastolic volume, k is a constant, and LV wall is the volume of the left ventricular wall) could predict rehospitalization in FMR patients after TEER.

Methods and results: M_wwas calculated for 24 FMR patients using echocardiography. The median left ventricular ejection fraction was 27% and the median M_wwas 32. Over a 498-day median follow-up period, 38% of patients were rehospitalized for heart failure, and only M_whad a high area under the curve in time-dependent receiver operating characteristic analysis.

Conclusions: M_wis an effective predictor for rehospitalization in FMR patients after TEER.

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来源期刊

Circulation Journal 医学-心血管系统

CiteScore

5.80

自引率

12.10%

发文量

471

审稿时长

1.6 months

期刊介绍： Circulation publishes original research manuscripts, review articles, and other content related to cardiovascular health and disease, including observational studies, clinical trials, epidemiology, health services and outcomes studies, and advances in basic and translational research.