Carolin Alexandra Boldt, Dirk Keiner, Norman Best, Thilo Bertsche
{"title":"患者对疼痛治疗中性别差异的态度和体验。","authors":"Carolin Alexandra Boldt, Dirk Keiner, Norman Best, Thilo Bertsche","doi":"10.3390/pharmacy12060175","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Biological, pharmacological, and socio-cultural aspects influence gender-specific effects in pain management.</p><p><strong>Methods: </strong>Gender-specific aspects of pain management were assessed in a rural outpatient center via semi-structured patient interview: (i) general gender aspects (total population) from 1 = \"fully disagree\" to 5 = \"fully agree\"; and (ii) individual pain (matched pairs) via numeric analog scale (NAS) from 0 = \"no pain\" to 10 = \"maximum pain\". Patient charts were assessed for pain management (WHO-ladder).</p><p><strong>Results: </strong>In total, 113 patients were enrolled (59.18 [SD: 12.76] years, 46% female, 54% male, 0% diverse), and 42 were matched into female-male pairs. (i) Women and men agreed that men and women should be treated equally despite biological differences (median: 5 [women] vs. 5 [men]; <i>p</i> = 0.789). As a reason for gender-specific aspects, \"medication concentration\" was reported more frequently by women (<i>p</i> = 0.038) and \"no answer\" by men (<i>p</i> = 0.014). (ii) Mean value (SD) of pain (NAS) was 4.0 (SD 2.3) for women and 3.3 (SD 2.6) for men (<i>p</i> = 0.215) with a positive correlation between pain management escalation (WHO-ladder) and the pain score (NAS) only in men (r = 0.704, <i>p</i> = 0.001). Women rather reported an influence of adverse drug reactions on treatment contentment than men (<i>p</i> = 0.042).</p><p><strong>Conclusions: </strong>Although patients pleaded for gender-independent equal treatment, gender-specific differences in pain therapy were found.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"12 6","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11587403/pdf/","citationCount":"0","resultStr":"{\"title\":\"Attitudes and Experiences of Patients Regarding Gender-Specific Aspects of Pain Management.\",\"authors\":\"Carolin Alexandra Boldt, Dirk Keiner, Norman Best, Thilo Bertsche\",\"doi\":\"10.3390/pharmacy12060175\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Biological, pharmacological, and socio-cultural aspects influence gender-specific effects in pain management.</p><p><strong>Methods: </strong>Gender-specific aspects of pain management were assessed in a rural outpatient center via semi-structured patient interview: (i) general gender aspects (total population) from 1 = \\\"fully disagree\\\" to 5 = \\\"fully agree\\\"; and (ii) individual pain (matched pairs) via numeric analog scale (NAS) from 0 = \\\"no pain\\\" to 10 = \\\"maximum pain\\\". Patient charts were assessed for pain management (WHO-ladder).</p><p><strong>Results: </strong>In total, 113 patients were enrolled (59.18 [SD: 12.76] years, 46% female, 54% male, 0% diverse), and 42 were matched into female-male pairs. (i) Women and men agreed that men and women should be treated equally despite biological differences (median: 5 [women] vs. 5 [men]; <i>p</i> = 0.789). As a reason for gender-specific aspects, \\\"medication concentration\\\" was reported more frequently by women (<i>p</i> = 0.038) and \\\"no answer\\\" by men (<i>p</i> = 0.014). (ii) Mean value (SD) of pain (NAS) was 4.0 (SD 2.3) for women and 3.3 (SD 2.6) for men (<i>p</i> = 0.215) with a positive correlation between pain management escalation (WHO-ladder) and the pain score (NAS) only in men (r = 0.704, <i>p</i> = 0.001). Women rather reported an influence of adverse drug reactions on treatment contentment than men (<i>p</i> = 0.042).</p><p><strong>Conclusions: </strong>Although patients pleaded for gender-independent equal treatment, gender-specific differences in pain therapy were found.</p>\",\"PeriodicalId\":30544,\"journal\":{\"name\":\"Pharmacy\",\"volume\":\"12 6\",\"pages\":\"\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2024-11-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11587403/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pharmacy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3390/pharmacy12060175\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmacy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/pharmacy12060175","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Attitudes and Experiences of Patients Regarding Gender-Specific Aspects of Pain Management.
Background: Biological, pharmacological, and socio-cultural aspects influence gender-specific effects in pain management.
Methods: Gender-specific aspects of pain management were assessed in a rural outpatient center via semi-structured patient interview: (i) general gender aspects (total population) from 1 = "fully disagree" to 5 = "fully agree"; and (ii) individual pain (matched pairs) via numeric analog scale (NAS) from 0 = "no pain" to 10 = "maximum pain". Patient charts were assessed for pain management (WHO-ladder).
Results: In total, 113 patients were enrolled (59.18 [SD: 12.76] years, 46% female, 54% male, 0% diverse), and 42 were matched into female-male pairs. (i) Women and men agreed that men and women should be treated equally despite biological differences (median: 5 [women] vs. 5 [men]; p = 0.789). As a reason for gender-specific aspects, "medication concentration" was reported more frequently by women (p = 0.038) and "no answer" by men (p = 0.014). (ii) Mean value (SD) of pain (NAS) was 4.0 (SD 2.3) for women and 3.3 (SD 2.6) for men (p = 0.215) with a positive correlation between pain management escalation (WHO-ladder) and the pain score (NAS) only in men (r = 0.704, p = 0.001). Women rather reported an influence of adverse drug reactions on treatment contentment than men (p = 0.042).
Conclusions: Although patients pleaded for gender-independent equal treatment, gender-specific differences in pain therapy were found.