{"title":"遵义市老年RA患者过去一年的情况如何?","authors":"Yong Chen, Yan-Juan Chen, Jian-Feng Luo, Mang He, Si-Jin Zhao, Shi-Dan Tian, Yong-Qiao Zhang, Xiao-Long Chen, Chuan-Jie Yang, Yu-Zhuo Luo, Kutty Selva Nandakumar, Mei Tian","doi":"10.2147/JIR.S493145","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>The quality of life (QoL) of elderly patients with rheumatoid arthritis (RA) in Zunyi China based on health parameters has not been previously analyzed. This study compares the 36-Item Short Form Health Survey (SF-36) scores and prevailing health complications between <60y and ≥60y patients with RA. Data from 1166 patients with RA who visited the rheumatology department of Zunyi Medical University Hospital were followed up and retrospectively analyzed.</p><p><strong>Patients and methods: </strong>Data from 1166 patients with RA who visited the rheumatology department of Zunyi Medical University Hospital (2021.1-2022.8) were followed up and retrospectively analyzed.</p><p><strong>Results: </strong>Twenty cases passed away at 61.55 ± 8.11y, which was 6.75 years less than the local average age of death. Elderly patients with RA reported lower recovery levels, and their levels of inflammatory markers such as Immunoglobulin M-rheumatoid factor (IgM-RF), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) levels were significantly higher than those of younger patients during their past one-year observation period. The SF-36 results indicated that eight items of QoL in the elderly patients were all significantly inferior to <60y patients, while the complications of interstitial lung disease (ILD), latent tuberculosis infection (LTBI) and, lung and herpes zoster infections were significantly higher.</p><p><strong>Conclusion: </strong>Elderly patients had a higher disease activity along with poor QoL, more health-related complications, and susceptibility to infections. Our study emphasizes the imperative need for optimization of RA treatment modalities in the elderly to alleviate their sufferings.</p>","PeriodicalId":16107,"journal":{"name":"Journal of Inflammation Research","volume":"17 ","pages":"8935-8944"},"PeriodicalIF":4.2000,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11584323/pdf/","citationCount":"0","resultStr":"{\"title\":\"How Were the Elderly RA Patients Doing Over the Past Year?-A Post Hoc Analysis for Telephone Based Following Up to RA Patients in Zunyi China.\",\"authors\":\"Yong Chen, Yan-Juan Chen, Jian-Feng Luo, Mang He, Si-Jin Zhao, Shi-Dan Tian, Yong-Qiao Zhang, Xiao-Long Chen, Chuan-Jie Yang, Yu-Zhuo Luo, Kutty Selva Nandakumar, Mei Tian\",\"doi\":\"10.2147/JIR.S493145\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>The quality of life (QoL) of elderly patients with rheumatoid arthritis (RA) in Zunyi China based on health parameters has not been previously analyzed. This study compares the 36-Item Short Form Health Survey (SF-36) scores and prevailing health complications between <60y and ≥60y patients with RA. Data from 1166 patients with RA who visited the rheumatology department of Zunyi Medical University Hospital were followed up and retrospectively analyzed.</p><p><strong>Patients and methods: </strong>Data from 1166 patients with RA who visited the rheumatology department of Zunyi Medical University Hospital (2021.1-2022.8) were followed up and retrospectively analyzed.</p><p><strong>Results: </strong>Twenty cases passed away at 61.55 ± 8.11y, which was 6.75 years less than the local average age of death. Elderly patients with RA reported lower recovery levels, and their levels of inflammatory markers such as Immunoglobulin M-rheumatoid factor (IgM-RF), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) levels were significantly higher than those of younger patients during their past one-year observation period. The SF-36 results indicated that eight items of QoL in the elderly patients were all significantly inferior to <60y patients, while the complications of interstitial lung disease (ILD), latent tuberculosis infection (LTBI) and, lung and herpes zoster infections were significantly higher.</p><p><strong>Conclusion: </strong>Elderly patients had a higher disease activity along with poor QoL, more health-related complications, and susceptibility to infections. Our study emphasizes the imperative need for optimization of RA treatment modalities in the elderly to alleviate their sufferings.</p>\",\"PeriodicalId\":16107,\"journal\":{\"name\":\"Journal of Inflammation Research\",\"volume\":\"17 \",\"pages\":\"8935-8944\"},\"PeriodicalIF\":4.2000,\"publicationDate\":\"2024-11-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11584323/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Inflammation Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2147/JIR.S493145\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"IMMUNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Inflammation Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2147/JIR.S493145","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
目的:此前尚未对遵义地区老年类风湿关节炎(RA)患者基于健康参数的生活质量(QoL)进行分析。本研究比较了类风湿关节炎患者的 36 项简表健康调查(SF-36)得分和普遍存在的健康并发症:对遵义医学院附属医院风湿免疫科就诊的1166例RA患者(2021.1-2022.8)的数据进行随访和回顾性分析:20例患者的死亡年龄为(61.55±8.11)岁,比当地平均死亡年龄低6.75岁。在过去一年的观察期间,老年 RA 患者的康复水平较低,其炎症指标如免疫球蛋白 M-类风湿因子(IgM-RF)、红细胞沉降率(ESR)和 C 反应蛋白(CRP)水平明显高于年轻患者。SF-36 结果显示,老年患者的 8 项 QoL 均明显低于结论:老年患者的疾病活动度较高,生活质量较差,健康相关并发症较多,易受感染。我们的研究强调,必须优化老年人的 RA 治疗方法,以减轻他们的痛苦。
How Were the Elderly RA Patients Doing Over the Past Year?-A Post Hoc Analysis for Telephone Based Following Up to RA Patients in Zunyi China.
Purpose: The quality of life (QoL) of elderly patients with rheumatoid arthritis (RA) in Zunyi China based on health parameters has not been previously analyzed. This study compares the 36-Item Short Form Health Survey (SF-36) scores and prevailing health complications between <60y and ≥60y patients with RA. Data from 1166 patients with RA who visited the rheumatology department of Zunyi Medical University Hospital were followed up and retrospectively analyzed.
Patients and methods: Data from 1166 patients with RA who visited the rheumatology department of Zunyi Medical University Hospital (2021.1-2022.8) were followed up and retrospectively analyzed.
Results: Twenty cases passed away at 61.55 ± 8.11y, which was 6.75 years less than the local average age of death. Elderly patients with RA reported lower recovery levels, and their levels of inflammatory markers such as Immunoglobulin M-rheumatoid factor (IgM-RF), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) levels were significantly higher than those of younger patients during their past one-year observation period. The SF-36 results indicated that eight items of QoL in the elderly patients were all significantly inferior to <60y patients, while the complications of interstitial lung disease (ILD), latent tuberculosis infection (LTBI) and, lung and herpes zoster infections were significantly higher.
Conclusion: Elderly patients had a higher disease activity along with poor QoL, more health-related complications, and susceptibility to infections. Our study emphasizes the imperative need for optimization of RA treatment modalities in the elderly to alleviate their sufferings.
期刊介绍:
An international, peer-reviewed, open access, online journal that welcomes laboratory and clinical findings on the molecular basis, cell biology and pharmacology of inflammation.