遵义市老年RA患者过去一年的情况如何?

IF 4.2 2区 医学 Q2 IMMUNOLOGY
Journal of Inflammation Research Pub Date : 2024-11-18 eCollection Date: 2024-01-01 DOI:10.2147/JIR.S493145
Yong Chen, Yan-Juan Chen, Jian-Feng Luo, Mang He, Si-Jin Zhao, Shi-Dan Tian, Yong-Qiao Zhang, Xiao-Long Chen, Chuan-Jie Yang, Yu-Zhuo Luo, Kutty Selva Nandakumar, Mei Tian
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引用次数: 0

摘要

目的:此前尚未对遵义地区老年类风湿关节炎(RA)患者基于健康参数的生活质量(QoL)进行分析。本研究比较了类风湿关节炎患者的 36 项简表健康调查(SF-36)得分和普遍存在的健康并发症:对遵义医学院附属医院风湿免疫科就诊的1166例RA患者(2021.1-2022.8)的数据进行随访和回顾性分析:20例患者的死亡年龄为(61.55±8.11)岁,比当地平均死亡年龄低6.75岁。在过去一年的观察期间,老年 RA 患者的康复水平较低,其炎症指标如免疫球蛋白 M-类风湿因子(IgM-RF)、红细胞沉降率(ESR)和 C 反应蛋白(CRP)水平明显高于年轻患者。SF-36 结果显示,老年患者的 8 项 QoL 均明显低于结论:老年患者的疾病活动度较高,生活质量较差,健康相关并发症较多,易受感染。我们的研究强调,必须优化老年人的 RA 治疗方法,以减轻他们的痛苦。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
How Were the Elderly RA Patients Doing Over the Past Year?-A Post Hoc Analysis for Telephone Based Following Up to RA Patients in Zunyi China.

Purpose: The quality of life (QoL) of elderly patients with rheumatoid arthritis (RA) in Zunyi China based on health parameters has not been previously analyzed. This study compares the 36-Item Short Form Health Survey (SF-36) scores and prevailing health complications between <60y and ≥60y patients with RA. Data from 1166 patients with RA who visited the rheumatology department of Zunyi Medical University Hospital were followed up and retrospectively analyzed.

Patients and methods: Data from 1166 patients with RA who visited the rheumatology department of Zunyi Medical University Hospital (2021.1-2022.8) were followed up and retrospectively analyzed.

Results: Twenty cases passed away at 61.55 ± 8.11y, which was 6.75 years less than the local average age of death. Elderly patients with RA reported lower recovery levels, and their levels of inflammatory markers such as Immunoglobulin M-rheumatoid factor (IgM-RF), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) levels were significantly higher than those of younger patients during their past one-year observation period. The SF-36 results indicated that eight items of QoL in the elderly patients were all significantly inferior to <60y patients, while the complications of interstitial lung disease (ILD), latent tuberculosis infection (LTBI) and, lung and herpes zoster infections were significantly higher.

Conclusion: Elderly patients had a higher disease activity along with poor QoL, more health-related complications, and susceptibility to infections. Our study emphasizes the imperative need for optimization of RA treatment modalities in the elderly to alleviate their sufferings.

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来源期刊
Journal of Inflammation Research
Journal of Inflammation Research Immunology and Microbiology-Immunology
CiteScore
6.10
自引率
2.20%
发文量
658
审稿时长
16 weeks
期刊介绍: An international, peer-reviewed, open access, online journal that welcomes laboratory and clinical findings on the molecular basis, cell biology and pharmacology of inflammation.
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