灰色地带的手术:SAVR 对 75 至 80 岁的患者是否仍然有用?

IF 1.6 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Ivo Deblier, Karl Dossche, Anthony Vanermen, Wilhelm Mistiaen
{"title":"灰色地带的手术:SAVR 对 75 至 80 岁的患者是否仍然有用?","authors":"Ivo Deblier, Karl Dossche, Anthony Vanermen, Wilhelm Mistiaen","doi":"10.1080/14796678.2024.2433827","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Aortic valve replacement is the only effective treatment for symptomatic aortic valve disease. Transcatheter implantation has been introduced as alternative for surgery (SAVR), but its penetration varied widely. For high-risk octogenarian patients, the advantages of TAVI are clear. Patients between 75 and 79 years of age could be considered as \"the gray zone.\"</p><p><strong>Methods: </strong>We compared the outcome of SAVR with or without concomitant procedures between patients younger than 75 versus 75-79 years for their preoperative profile, operative parameters, and postoperative outcomes.</p><p><strong>Results: </strong>Older patients had a higher risk score with more cardiovascular comorbidity and renal dysfunction. They required more concomitant CABG but less mitral valve repair. Cardiopulmonary bypass time was similar. In-hospital complication rates, need for blood transfusion, and length of stay in intensive care unit were higher in older patients. Thirty-day mortality was not significantly increased, Euroscore II overestimated mortality in both age groups. Age over 75 years was not an independent predictor for mortality. Need for emergent SAVR was only predictive in the older group. Long-term survival was acceptable. Age over 75 years was not the dominant predictor.</p><p><strong>Conclusions: </strong>SAVR remains a valid option to treat symptomatic aortic valve disease in the age group of 75-79.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"1-10"},"PeriodicalIF":1.6000,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Operation in the gray zone: is SAVR still useful in patients aged between 75 and 80 years?\",\"authors\":\"Ivo Deblier, Karl Dossche, Anthony Vanermen, Wilhelm Mistiaen\",\"doi\":\"10.1080/14796678.2024.2433827\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Aortic valve replacement is the only effective treatment for symptomatic aortic valve disease. Transcatheter implantation has been introduced as alternative for surgery (SAVR), but its penetration varied widely. For high-risk octogenarian patients, the advantages of TAVI are clear. Patients between 75 and 79 years of age could be considered as \\\"the gray zone.\\\"</p><p><strong>Methods: </strong>We compared the outcome of SAVR with or without concomitant procedures between patients younger than 75 versus 75-79 years for their preoperative profile, operative parameters, and postoperative outcomes.</p><p><strong>Results: </strong>Older patients had a higher risk score with more cardiovascular comorbidity and renal dysfunction. They required more concomitant CABG but less mitral valve repair. Cardiopulmonary bypass time was similar. In-hospital complication rates, need for blood transfusion, and length of stay in intensive care unit were higher in older patients. Thirty-day mortality was not significantly increased, Euroscore II overestimated mortality in both age groups. Age over 75 years was not an independent predictor for mortality. Need for emergent SAVR was only predictive in the older group. Long-term survival was acceptable. Age over 75 years was not the dominant predictor.</p><p><strong>Conclusions: </strong>SAVR remains a valid option to treat symptomatic aortic valve disease in the age group of 75-79.</p>\",\"PeriodicalId\":12589,\"journal\":{\"name\":\"Future cardiology\",\"volume\":\" \",\"pages\":\"1-10\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2024-11-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Future cardiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/14796678.2024.2433827\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future cardiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/14796678.2024.2433827","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0

摘要

简介:主动脉瓣置换术是治疗无症状主动脉瓣疾病的唯一有效方法:主动脉瓣置换术是治疗无症状主动脉瓣疾病的唯一有效方法。经导管植入术作为手术(SAVR)的替代疗法已经问世,但其普及率参差不齐。对于高风险的八旬患者,经导管主动脉瓣置换术的优势显而易见。75至79岁的患者可被视为 "灰色地带":我们比较了 75 岁以下患者与 75-79 岁患者在接受或不接受同期手术的情况下进行 SAVR 的术前情况、手术参数和术后结果:结果:老年患者的风险评分较高,心血管合并症和肾功能不全的情况较多。他们需要同时进行更多的心血管造影术,但二尖瓣修复术较少。心肺旁路时间相似。高龄患者的院内并发症发生率、输血需求和重症监护室住院时间更长。30天死亡率没有明显增加,Euroscore II高估了两个年龄组的死亡率。年龄超过75岁并不是死亡率的独立预测因素。只有年龄较大的患者才需要进行紧急 SAVR。长期存活率尚可。年龄超过75岁并不是主要的预测因素:结论:SAVR仍是治疗75-79岁年龄组无症状主动脉瓣疾病的有效选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Operation in the gray zone: is SAVR still useful in patients aged between 75 and 80 years?

Introduction: Aortic valve replacement is the only effective treatment for symptomatic aortic valve disease. Transcatheter implantation has been introduced as alternative for surgery (SAVR), but its penetration varied widely. For high-risk octogenarian patients, the advantages of TAVI are clear. Patients between 75 and 79 years of age could be considered as "the gray zone."

Methods: We compared the outcome of SAVR with or without concomitant procedures between patients younger than 75 versus 75-79 years for their preoperative profile, operative parameters, and postoperative outcomes.

Results: Older patients had a higher risk score with more cardiovascular comorbidity and renal dysfunction. They required more concomitant CABG but less mitral valve repair. Cardiopulmonary bypass time was similar. In-hospital complication rates, need for blood transfusion, and length of stay in intensive care unit were higher in older patients. Thirty-day mortality was not significantly increased, Euroscore II overestimated mortality in both age groups. Age over 75 years was not an independent predictor for mortality. Need for emergent SAVR was only predictive in the older group. Long-term survival was acceptable. Age over 75 years was not the dominant predictor.

Conclusions: SAVR remains a valid option to treat symptomatic aortic valve disease in the age group of 75-79.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Future cardiology
Future cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
2.80
自引率
5.90%
发文量
87
期刊介绍: Research advances have contributed to improved outcomes across all specialties, but the rate of advancement in cardiology has been exceptional. Concurrently, the population of patients with cardiac conditions continues to grow and greater public awareness has increased patients" expectations of new drugs and devices. Future Cardiology (ISSN 1479-6678) reflects this new era of cardiology and highlights the new molecular approach to advancing cardiovascular therapy. Coverage will also reflect the major technological advances in bioengineering in cardiology in terms of advanced and robust devices, miniaturization, imaging, system modeling and information management issues.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信