微流控数据驱动模型：简评。

IF 2.4 4区工程技术 Q2 BIOCHEMICAL RESEARCH METHODS

Biomicrofluidics Pub Date : 2024-11-20 eCollection Date: 2024-12-01 DOI:10.1063/5.0236407

Yu Chang, Qichen Shang, Zifei Yan, Jian Deng, Guangsheng Luo

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引用次数: 0

摘要

微流控设备在各个领域都有许多独特的实际应用，因此为这些设备开发精确的模型非常重要，目前已开发出许多不同的模型。现有的建模方法主要包括机理推导法和半经验相关法，但这两种方法都不具有普遍适用性。为了实现更准确、更普遍的建模过程，最近人们开始研究使用数据驱动建模。本综述重点介绍了应用数据驱动建模技术模拟和设计微流控器件的最新进展。首先，它介绍了传统建模方法在微流控技术中的应用；随后，通过不同的数据库资源，分三类综述了数据驱动建模的研究；最后，它提出了一些需要进一步研究的开放性问题。

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Data-driven models for microfluidics: A short review.

Microfluidic devices have many unique practical applications across a wide range of fields, making it important to develop accurate models of these devices, and many different models have been developed. Existing modeling methods mainly include mechanism derivation and semi-empirical correlations, but both are not universally applicable. In order to achieve a more accurate and general modeling process, the use of data-driven modeling has been studied recently. This review highlights recent advances in the application of data-driven modeling techniques for simulating and designing microfluidic devices. First, it introduces the application of traditional modeling approaches in microfluidics; subsequently, through different database sources, it reviews studies on data-driven modeling in three categories; and finally, it raises some open issues that require further investigation.

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来源期刊

Biomicrofluidics 生物-纳米科技

CiteScore

5.80

自引率

3.10%

发文量

审稿时长

1.3 months

期刊介绍： Biomicrofluidics (BMF) is an online-only journal published by AIP Publishing to rapidly disseminate research in fundamental physicochemical mechanisms associated with microfluidic and nanofluidic phenomena. BMF also publishes research in unique microfluidic and nanofluidic techniques for diagnostic, medical, biological, pharmaceutical, environmental, and chemical applications. BMF offers quick publication, multimedia capability, and worldwide circulation among academic, national, and industrial laboratories. With a primary focus on high-quality original research articles, BMF also organizes special sections that help explain and define specific challenges unique to the interdisciplinary field of biomicrofluidics. Microfluidic and nanofluidic actuation (electrokinetics, acoustofluidics, optofluidics, capillary) Liquid Biopsy (microRNA profiling, circulating tumor cell isolation, exosome isolation, circulating tumor DNA quantification) Cell sorting, manipulation, and transfection (di/electrophoresis, magnetic beads, optical traps, electroporation) Molecular Separation and Concentration (isotachophoresis, concentration polarization, di/electrophoresis, magnetic beads, nanoparticles) Cell culture and analysis(single cell assays, stimuli response, stem cell transfection) Genomic and proteomic analysis (rapid gene sequencing, DNA/protein/carbohydrate arrays) Biosensors (immuno-assay, nucleic acid fluorescent assay, colorimetric assay, enzyme amplification, plasmonic and Raman nano-reporter, molecular beacon, FRET, aptamer, nanopore, optical fibers) Biophysical transport and characterization (DNA, single protein, ion channel and membrane dynamics, cell motility and communication mechanisms, electrophysiology, patch clamping). Etc...