基于 MCM-41 的分散微固相萃取技术在液相色谱定量前萃取水样中的部分头孢菌素类抗生素残留物

IF 4.1 Q1 CHEMISTRY, ANALYTICAL
Andisiwe Bangani , Mthokozisi Mnguni , Thollwana Andretta Makhetha , Elisabete Oliveira , José Luis Capelo-Martínez , Carlos Lodeiro , Philiswa Nosizo Nomngongo
{"title":"基于 MCM-41 的分散微固相萃取技术在液相色谱定量前萃取水样中的部分头孢菌素类抗生素残留物","authors":"Andisiwe Bangani ,&nbsp;Mthokozisi Mnguni ,&nbsp;Thollwana Andretta Makhetha ,&nbsp;Elisabete Oliveira ,&nbsp;José Luis Capelo-Martínez ,&nbsp;Carlos Lodeiro ,&nbsp;Philiswa Nosizo Nomngongo","doi":"10.1016/j.talo.2024.100382","DOIUrl":null,"url":null,"abstract":"<div><div>The occurrence of antibiotics in water bodies is of concern owing to the serious risk they pose to the environment, water security, aquatic organisms, and human health. In this study, mesoporous silica (MCM-41) nanostructured material was synthesised and characterized by various analytical techniques to determine its morphology and dimension, functional groups, surface charge, and textural properties. The nanostructured MCM-41 was used as an adsorbent in ultrasound-assisted dispersive micro solid-phase extraction (UA-D-µ-SPE) of cefadroxil (CFDX) and cephalexin (CPLX) in water samples. The concentration of the analytes in aqueous solution and real water samples was determined using high-performance liquid chromatography coupled with diode array detection (HPLC-DAD). The developed method for CFDX and CPLX in various water samples exhibited relative linear ranges of 0.1–600 µg/L and 0.1–550 µg/L, respectively, and correlation coefficients ranging from 0.9923–0.9993. Under optimum condition, the UA-D-µ-SPE/HPLC-DAD method displayed low limits of detection (LOD) and quantification (LOQ), with values ranging from 0.02–0.16 µg/L and 0.067–0.53 µg/L, respectively. The investigated intraday and interday accuracy in spiked water samples showed acceptable extraction efficiencies with a range of 73.5–98.1% and a relative standard deviation less than 6.0%. Moreover, the performance of MCM-41 was also assessed for the removal of cephalosporin antibiotics aqueous solutions. The kinetic and isotherm studies revealed that the adsorption process followed pseudo-second order and the Langmuir model, respectively. Furthermore, the maximum adsorption capacities for CFDX and CPLX were 43.2 and 47.8 mg/g. Lastly, the UA-D-µ-SPE/HPLC-DAD method was successfully applied in extracting, preconcentrating, separating and determining CFDX and CPLX in wastewater and surface water samples. These results demonstrated that MCM-41 can be applied in the removal of cephalosporin antibiotics from aquatic environments.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"10 ","pages":"Article 100382"},"PeriodicalIF":4.1000,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"MCM-41 based dispersive micro-solid phase extraction of selected cephalosporin antibiotic residues from water samples prior to liquid chromatographic quantification\",\"authors\":\"Andisiwe Bangani ,&nbsp;Mthokozisi Mnguni ,&nbsp;Thollwana Andretta Makhetha ,&nbsp;Elisabete Oliveira ,&nbsp;José Luis Capelo-Martínez ,&nbsp;Carlos Lodeiro ,&nbsp;Philiswa Nosizo Nomngongo\",\"doi\":\"10.1016/j.talo.2024.100382\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>The occurrence of antibiotics in water bodies is of concern owing to the serious risk they pose to the environment, water security, aquatic organisms, and human health. In this study, mesoporous silica (MCM-41) nanostructured material was synthesised and characterized by various analytical techniques to determine its morphology and dimension, functional groups, surface charge, and textural properties. The nanostructured MCM-41 was used as an adsorbent in ultrasound-assisted dispersive micro solid-phase extraction (UA-D-µ-SPE) of cefadroxil (CFDX) and cephalexin (CPLX) in water samples. The concentration of the analytes in aqueous solution and real water samples was determined using high-performance liquid chromatography coupled with diode array detection (HPLC-DAD). The developed method for CFDX and CPLX in various water samples exhibited relative linear ranges of 0.1–600 µg/L and 0.1–550 µg/L, respectively, and correlation coefficients ranging from 0.9923–0.9993. Under optimum condition, the UA-D-µ-SPE/HPLC-DAD method displayed low limits of detection (LOD) and quantification (LOQ), with values ranging from 0.02–0.16 µg/L and 0.067–0.53 µg/L, respectively. The investigated intraday and interday accuracy in spiked water samples showed acceptable extraction efficiencies with a range of 73.5–98.1% and a relative standard deviation less than 6.0%. Moreover, the performance of MCM-41 was also assessed for the removal of cephalosporin antibiotics aqueous solutions. The kinetic and isotherm studies revealed that the adsorption process followed pseudo-second order and the Langmuir model, respectively. Furthermore, the maximum adsorption capacities for CFDX and CPLX were 43.2 and 47.8 mg/g. Lastly, the UA-D-µ-SPE/HPLC-DAD method was successfully applied in extracting, preconcentrating, separating and determining CFDX and CPLX in wastewater and surface water samples. These results demonstrated that MCM-41 can be applied in the removal of cephalosporin antibiotics from aquatic environments.</div></div>\",\"PeriodicalId\":436,\"journal\":{\"name\":\"Talanta Open\",\"volume\":\"10 \",\"pages\":\"Article 100382\"},\"PeriodicalIF\":4.1000,\"publicationDate\":\"2024-11-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Talanta Open\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2666831924000961\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Talanta Open","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666831924000961","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0

摘要

由于抗生素对环境、水安全、水生生物和人类健康构成严重威胁,水体中抗生素的出现令人担忧。本研究合成了介孔二氧化硅(MCM-41)纳米结构材料,并通过各种分析技术确定了其形态和尺寸、官能团、表面电荷和纹理特性。纳米结构 MCM-41 被用作超声辅助分散微固相萃取(UA-D-µ-SPE)的吸附剂,用于萃取水样中的头孢羟氨苄(CFDX)和头孢氨苄(CPLX)。采用高效液相色谱-二极管阵列检测法(HPLC-DAD)测定了水溶液和实际水样中分析物的浓度。所建立的方法在不同水样中CFDX和CPLX的相对线性范围分别为0.1-600 µg/L和0.1-550 µg/L,相关系数为0.9923-0.9993。在最佳条件下,UA-D-µ-SPE/HPLC-DAD 方法的检出限(LOD)和定量限(LOQ)较低,分别为 0.02-0.16 µg/L 和 0.067-0.53 µg/L。在加标水样中进行的日内和日间准确度调查显示,萃取效率在 73.5-98.1% 之间,相对标准偏差小于 6.0%。此外,还评估了 MCM-41 去除头孢类抗生素水溶液的性能。动力学和等温线研究表明,吸附过程分别遵循伪二阶和 Langmuir 模型。此外,CFDX 和 CPLX 的最大吸附容量分别为 43.2 和 47.8 毫克/克。最后,UA-D-µ-SPE/HPLC-DAD 方法成功地用于提取、预浓缩、分离和测定废水和地表水样品中的 CFDX 和 CPLX。这些结果表明,MCM-41 可用于去除水生环境中的头孢类抗生素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

MCM-41 based dispersive micro-solid phase extraction of selected cephalosporin antibiotic residues from water samples prior to liquid chromatographic quantification

MCM-41 based dispersive micro-solid phase extraction of selected cephalosporin antibiotic residues from water samples prior to liquid chromatographic quantification
The occurrence of antibiotics in water bodies is of concern owing to the serious risk they pose to the environment, water security, aquatic organisms, and human health. In this study, mesoporous silica (MCM-41) nanostructured material was synthesised and characterized by various analytical techniques to determine its morphology and dimension, functional groups, surface charge, and textural properties. The nanostructured MCM-41 was used as an adsorbent in ultrasound-assisted dispersive micro solid-phase extraction (UA-D-µ-SPE) of cefadroxil (CFDX) and cephalexin (CPLX) in water samples. The concentration of the analytes in aqueous solution and real water samples was determined using high-performance liquid chromatography coupled with diode array detection (HPLC-DAD). The developed method for CFDX and CPLX in various water samples exhibited relative linear ranges of 0.1–600 µg/L and 0.1–550 µg/L, respectively, and correlation coefficients ranging from 0.9923–0.9993. Under optimum condition, the UA-D-µ-SPE/HPLC-DAD method displayed low limits of detection (LOD) and quantification (LOQ), with values ranging from 0.02–0.16 µg/L and 0.067–0.53 µg/L, respectively. The investigated intraday and interday accuracy in spiked water samples showed acceptable extraction efficiencies with a range of 73.5–98.1% and a relative standard deviation less than 6.0%. Moreover, the performance of MCM-41 was also assessed for the removal of cephalosporin antibiotics aqueous solutions. The kinetic and isotherm studies revealed that the adsorption process followed pseudo-second order and the Langmuir model, respectively. Furthermore, the maximum adsorption capacities for CFDX and CPLX were 43.2 and 47.8 mg/g. Lastly, the UA-D-µ-SPE/HPLC-DAD method was successfully applied in extracting, preconcentrating, separating and determining CFDX and CPLX in wastewater and surface water samples. These results demonstrated that MCM-41 can be applied in the removal of cephalosporin antibiotics from aquatic environments.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Talanta Open
Talanta Open Chemistry-Analytical Chemistry
CiteScore
5.20
自引率
0.00%
发文量
86
审稿时长
49 days
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信