血红蛋白：通过生物催化多米诺策略绿色合成喹唑啉衍生物的高效氧化酶

IF 3.9 2区化学 Q2 CHEMISTRY, PHYSICAL

Molecular Catalysis Pub Date : 2024-11-21 DOI:10.1016/j.mcat.2024.114680

Shenhan Xie , Chenyi Zhang , Yihang Dai , Fengxi Li , Lei Wang , Peng Chen , Zhi Wang

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引用次数: 0

摘要

本研究利用血红蛋白作为一种有效的氧化酶，通过促进生物催化多米诺反应，绿色合成喹唑啉衍生物。该反应具有广泛的底物范围，并与多种官能团具有良好的兼容性。此外，在既定条件下，还能以高产率获得所需的产物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Hemoglobin: An efficient oxidase for the green synthesis of quinazoline derivatives by biocatalytic domino strategy

In this study, hemoglobin was employed as an effective oxidase for the green synthesis of quinazoline derivatives by facilitating the biocatalytic domino reaction. This reaction exhibits a broad substrate scope and shows excellent compatibility with a variety of functional groups. Furthermore, the desired products were achieved with high yields under the established conditions.

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来源期刊

Molecular Catalysis Chemical Engineering-Process Chemistry and Technology

CiteScore

6.90

自引率

10.90%

发文量

700

审稿时长

40 days

期刊介绍： Molecular Catalysis publishes full papers that are original, rigorous, and scholarly contributions examining the molecular and atomic aspects of catalytic activation and reaction mechanisms. The fields covered are: Heterogeneous catalysis including immobilized molecular catalysts Homogeneous catalysis including organocatalysis, organometallic catalysis and biocatalysis Photo- and electrochemistry Theoretical aspects of catalysis analyzed by computational methods