伴有肠套叠的迟发性孤立 ICI(pembrolizumab)相关性胃炎

Rhode Island medical journal (2013) Pub Date : 2024-12-02
Casey Reed, Yousef Elfanagely, May Min
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引用次数: 0

摘要

免疫检查点抑制剂越来越多地用于治疗多种恶性肿瘤,但已知其具有发生免疫相关不良事件(irAEs)的风险。IrAEs涉及多种受影响的器官系统和症状。虽然胃肠道系统是常见的受影响系统,但孤立性胃炎的诊断并不常见。我们介绍了一名因服用抗程序性细胞死亡-1 抗体--pembrolizumab 而引起的孤立性 ICI 相关性胃炎并发肠套叠的患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Delayed-Onset Isolated ICI (pembrolizumab)-Associated Gastritis with Concomitant Intussusception.

Immune checkpoint inhibitors are increasingly used in the treatment of a number of malignancies and carry a known risk of immune-related adverse events (irAEs). IrAEs cover a broad range of affected organ systems and presenting symptoms. While the gastrointestinal system is a commonly affected system, isolated gastritis is an uncommon diagnosis. We present a patient with isolated ICI-related gastritis presenting with concomitant intussusception caused by the anti-programmed cell death-1 antibody, pembrolizumab.

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