将具有抗氧化/抗细胞凋亡作用的药用植物或生物活性成分作为预防和治疗心力衰竭的潜在治疗方法：文献综述。

IF 1.3 3区医学 Q3 CHEMISTRY, APPLIED

Journal of Asian Natural Products Research Pub Date : 2024-11-22 DOI:10.1080/10286020.2024.2414196

Atefeh Jalali, Maryam Kabiri, Shima Hashemi, Alireza Abdi Ardekani, Mohammad M Zarshenas

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引用次数: 0

摘要

心力衰竭是一种复杂的综合征，据估计，2019 年全球有 5620 万人患有心力衰竭。氧化应激和细胞凋亡通过靶向心脏细胞中的几种信号通路，对高血压的发展起着重要作用。本研究调查了对心房颤动治疗有积极作用的药用植物或其生物活性成分。在这项研究中，从 1990 年到 2023 年，我们通过流行数据库同步检索了 "心衰"、"植物"、"抗氧化 "或 "自由基清除"、"草药 "和 "细胞凋亡 "等关键词。最后，检索了氧化应激和细胞凋亡在心力衰竭发病中的作用，并研究了相关的信号通路。

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Medicinal plants or bioactive components with antioxidant/anti-apoptotic effects as a potential therapeutic approach in heart failure prevention and management: a literature review.

Heart failure is described as a complicated syndrome, which is estimated that 56.2 million people were living with HF globally in 2019. Oxidative stress and apoptosis play a major role on HF development via targeting several signaling pathways in cardiac cells. This study investigated medicinal plants or their bioactive components with positive effects on HF management. In this research, keywords "heart failure," "plant," "antioxidant" or "radical scavenging," "herbal" and "apoptosis" were synchronously searched through popular databases from 1990 up to 2023. Finally, the role of oxidative stress and apoptosis in HF development was searched and related signaling pathways were investigated.

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来源期刊

Journal of Asian Natural Products Research 医学-药学

CiteScore

3.20

自引率

5.90%

发文量

审稿时长

2.3 months

期刊介绍： The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures. All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.