骨骼肌 31P MR 光谱在预测肝移植后患者存活率方面优于 CT

IF 8.9 1区医学

Journal of Cachexia, Sarcopenia and Muscle Pub Date : 2024-11-23 DOI:10.1002/jcsm.13635

Denisa Kyselova, Irena Mikova, Petr Sedivy, Monika Dezortova, Milan Hajek, Jan Mares, Marek Tupy, Dana Kautznerova, Marek Kysela, Jiri Fronek, Julius Spicak, Pavel Trunecka

{"title":"骨骼肌 31P MR 光谱在预测肝移植后患者存活率方面优于 CT","authors":"Denisa Kyselova, Irena Mikova, Petr Sedivy, Monika Dezortova, Milan Hajek, Jan Mares, Marek Tupy, Dana Kautznerova, Marek Kysela, Jiri Fronek, Julius Spicak, Pavel Trunecka","doi":"10.1002/jcsm.13635","DOIUrl":null,"url":null,"abstract":"Skeletal muscle alterations are associated with higher mortality and morbidity in patients with liver cirrhosis. Assessing these changes seems to be a promising method for identifying patients at a high risk of poor outcomes following liver transplantation (LT). This is particularly important given the current global shortage of organ donors. However, evidence of the impact of these alterations on the prognosis of patients undergoing LT is inconclusive. The aim of our prospective study was to evaluate the impact of skeletal muscle changes, reflected in sarcopenia, myosteatosis and metabolic changes in the calf muscles, on perioperative outcomes and long-term survival after LT. We also sought to determine the posttransplant evolution of the resting muscle metabolism.","PeriodicalId":186,"journal":{"name":"Journal of Cachexia, Sarcopenia and Muscle","volume":"59 1","pages":""},"PeriodicalIF":8.9000,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Skeletal Muscle 31P MR Spectroscopy Surpasses CT in Predicting Patient Survival After Liver Transplantation\",\"authors\":\"Denisa Kyselova, Irena Mikova, Petr Sedivy, Monika Dezortova, Milan Hajek, Jan Mares, Marek Tupy, Dana Kautznerova, Marek Kysela, Jiri Fronek, Julius Spicak, Pavel Trunecka\",\"doi\":\"10.1002/jcsm.13635\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Skeletal muscle alterations are associated with higher mortality and morbidity in patients with liver cirrhosis. Assessing these changes seems to be a promising method for identifying patients at a high risk of poor outcomes following liver transplantation (LT). This is particularly important given the current global shortage of organ donors. However, evidence of the impact of these alterations on the prognosis of patients undergoing LT is inconclusive. The aim of our prospective study was to evaluate the impact of skeletal muscle changes, reflected in sarcopenia, myosteatosis and metabolic changes in the calf muscles, on perioperative outcomes and long-term survival after LT. We also sought to determine the posttransplant evolution of the resting muscle metabolism.\",\"PeriodicalId\":186,\"journal\":{\"name\":\"Journal of Cachexia, Sarcopenia and Muscle\",\"volume\":\"59 1\",\"pages\":\"\"},\"PeriodicalIF\":8.9000,\"publicationDate\":\"2024-11-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Cachexia, Sarcopenia and Muscle\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/jcsm.13635\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cachexia, Sarcopenia and Muscle","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/jcsm.13635","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

骨骼肌的改变与肝硬化患者较高的死亡率和发病率有关。评估这些变化似乎是鉴别肝移植（LT）后不良预后高风险患者的一种有前途的方法。在目前全球器官捐献者短缺的情况下，这一点尤为重要。然而，这些变化对接受肝移植患者预后的影响尚无定论。我们的前瞻性研究旨在评估骨骼肌变化（反映在肌肉疏松症、肌骨质疏松症和小腿肌肉的新陈代谢变化）对 LT 围手术期预后和长期存活率的影响。我们还试图确定移植后静止肌肉代谢的变化情况。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Skeletal Muscle 31P MR Spectroscopy Surpasses CT in Predicting Patient Survival After Liver Transplantation

Skeletal muscle alterations are associated with higher mortality and morbidity in patients with liver cirrhosis. Assessing these changes seems to be a promising method for identifying patients at a high risk of poor outcomes following liver transplantation (LT). This is particularly important given the current global shortage of organ donors. However, evidence of the impact of these alterations on the prognosis of patients undergoing LT is inconclusive. The aim of our prospective study was to evaluate the impact of skeletal muscle changes, reflected in sarcopenia, myosteatosis and metabolic changes in the calf muscles, on perioperative outcomes and long-term survival after LT. We also sought to determine the posttransplant evolution of the resting muscle metabolism.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of Cachexia, Sarcopenia and Muscle Medicine-Orthopedics and Sports Medicine

自引率

12.40%

发文量

期刊介绍： The Journal of Cachexia, Sarcopenia, and Muscle is a prestigious, peer-reviewed international publication committed to disseminating research and clinical insights pertaining to cachexia, sarcopenia, body composition, and the physiological and pathophysiological alterations occurring throughout the lifespan and in various illnesses across the spectrum of life sciences. This journal serves as a valuable resource for physicians, biochemists, biologists, dieticians, pharmacologists, and students alike.