加纳阿散蒂地区两个快速城市化地区与恶性疟原虫疟疾相关的社会人口因素、住房特征和临床症状。

IF 2.4 3区 医学 Q3 INFECTIOUS DISEASES
Stephen Opoku Afriyie, Kwasi Baako Antwi, Abdul-Hakim Mutala, Dawood Ackom Abbas, Kofi Agyapong Addo, Austine Tweneboah, Thomas Kwame Addison, Eric Osei, Cristian Koepfli, Kingsley Badu
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引用次数: 0

摘要

背景:疟疾被描述为一种贫困疾病,影响着通常生活在农村地区的最贫困人口。随着迄今为止农村地区向半城市环境过渡,本研究调查了加纳阿散蒂地区两个快速城市化地区恶性疟原虫疟疾的流行情况及相关风险因素:在加纳阿散蒂地区的阿戈纳和曼克兰索政府医院进行了一项横断面医院研究,这两个医院分别位于塞基尔南区和阿哈福阿诺西南区。从疑似疟疾患者身上抽取 5 µL 静脉血,使用快速诊断测试 (RDT) 进行疟疾检测。通过结构化问卷收集了有关社会人口因素、临床症状和住房特征的数据。为确定与疟疾相关的风险因素,进行了单变量和多变量逻辑回归分析:2021 年 1 月至 6 月期间,共有 1739 人参加了研究,中位年龄为 22 岁(IQR = 6-36)。总体疟疾发病率为 24.8%。与大于 30 岁的人相比,0 至 5 岁儿童(aOR = 3.36)和 6 至 14 岁儿童(aOR = 6.71)的疟疾检测呈阳性的几率分别高出三倍和六倍。同样,与其他职业相比,务农(aOR = 1.74)、居住在积水附近(aOR = 1.34)、发冷(aOR = 1.5)和呕吐(aOR = 1.93)与感染疟疾的几率增加有关。屋顶天花板(aOR = 0.66)和屏蔽门(aOR = 0.75)与疟疾感染风险降低有关。然而,睡在驱虫蚊帐(ITN)下、使用蚊香/驱蚊剂和室内滞留喷洒(IRS)与感染没有明显的统计学关系:结论:0 至 5 岁儿童和 6 至 14 岁儿童仍然是疟疾的高发人群。在这些迅速城市化的地区,应鼓励努力改善住房条件,如安装屋顶天花板、屏蔽门和清除潜在的蚊子滋生地。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Socio-demographic factors, housing characteristics, and clinical symptoms associated with falciparum malaria in two rapidly urbanizing areas in the Ashanti region of Ghana.

Background: Malaria has been described as a disease of poverty, affecting the poorest populations typically living in rural areas. As hitherto rural areas transition into semi-urban environments, this study investigated the prevalence of falciparum malaria and associated risk factors in two rapidly urbanizing districts in the Ashanti Region of Ghana.

Methods: A cross-sectional, hospital-based study was conducted at Agona and Mankranso Government Hospitals located within the Sekyere South and Ahafo Ano Southwest districts respectively, in the Ashanti Region of Ghana. Five µL of venous blood was obtained from suspected malaria patients and tested for malaria using rapid diagnostic test (RDT). Data on socio-demographic factors, clinical symptoms, and housing characteristics were collected using a structured questionnaire. Univariate and multivariate logistic regression analysis were performed to identify risk factors associated with malaria.

Results: A total of 1739 participants were enrolled in the study between January and June 2021 with median age of 22 years (IQR = 6-36). Overall malaria prevalence was 24.8%. Compared to > 30-year-olds, children between 0 and 5 years (aOR = 3.36) and those aged between 6 and 14 (aOR = 6.71) were three and six times more likely to test positive for malaria, respectively. Similarly, farming (aOR = 1.74), compared to other occupations, living close to stagnant water (aOR = 1.34), experiencing chills (aOR = 1.5), and vomiting (aOR = 1.93) were associated with increased odds of malaria infection. Having roofing ceiling (aOR = 0.66) and screened doors (aOR = 0.75) were associated with decreased risk of malaria. However, sleeping under insecticide-treated nets (ITNs), using mosquito coils/repellents, and indoor residual spraying (IRS) were not statistically significantly associated with infection.

Conclusion: Children between 0 and 5 years and those aged between 6 and 14 years continue to shoulder the highest burden of malaria. Efforts to improve housing characteristics such as installation of roofing ceiling, screening doors, and clearing potential mosquito breeding sites should be encouraged in these rapidly urbanizing areas.

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来源期刊
Malaria Journal
Malaria Journal 医学-寄生虫学
CiteScore
5.10
自引率
23.30%
发文量
334
审稿时长
2-4 weeks
期刊介绍: Malaria Journal is aimed at the scientific community interested in malaria in its broadest sense. It is the only journal that publishes exclusively articles on malaria and, as such, it aims to bring together knowledge from the different specialities involved in this very broad discipline, from the bench to the bedside and to the field.
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