噪声电前庭刺激对外侧前庭脊束兴奋性的神经干扰效应

IF 3.7 3区医学 Q1 CLINICAL NEUROLOGY

Clinical Neurophysiology Pub Date : 2024-11-15 DOI:10.1016/j.clinph.2024.11.002

Tsubasa Mitsutake , Hisato Nakazono , Tomoyuki Shiozaki , Takanori Taniguchi , Hisayoshi Yoshizuka , Maiko Sakamoto

{"title":"噪声电前庭刺激对外侧前庭脊束兴奋性的神经干扰效应","authors":"Tsubasa Mitsutake , Hisato Nakazono , Tomoyuki Shiozaki , Takanori Taniguchi , Hisayoshi Yoshizuka , Maiko Sakamoto","doi":"10.1016/j.clinph.2024.11.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>Noisy galvanic vestibular stimulation (GVS) using weak random noise waveforms enhances postural stability by modulating vestibular-related neural networks. This study aimed to investigate the neural interference mechanisms of noisy GVS on lateral vestibulospinal tract (LVST) excitability.</div></div><div><h3>Methods</h3><div>Twenty-six healthy volunteers were randomly divided into two groups: balance training combined with noisy GVS and sham GVS. Participants performed 10-minute balance training while standing on a soft foam surface with their eyes closed while adapting to each electrical stimulus. LVST excitability was assessed by measuring the soleus H-reflex following square-wave pulse GVS. Postural stability was measured by assessing the center of foot pressure sway while standing on a foam surface with eyes closed.</div></div><div><h3>Results</h3><div>The noisy GVS group showed significantly increased post-intervention H-reflex amplitude. The sham GVS group showed no significant difference in H-reflex amplitude pre- and post-intervention. The average sway velocity in the noisy and sham GVS groups significantly decreased in the medial–lateral direction of the center of foot pressure.</div></div><div><h3>Conclusions</h3><div>Noisy GVS may enhance LVST excitability and decrease body sway via vestibular system interference during holding upright, which relies heavily on vestibular sensations.</div></div><div><h3>Significance</h3><div>These findings may help understand the neural mechanisms of noisy GVS in neurorehabilitation.</div></div>","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"168 ","pages":"Pages 153-160"},"PeriodicalIF":3.7000,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Neural interference effects on lateral vestibulospinal tract excitability by noisy galvanic vestibular stimulation\",\"authors\":\"Tsubasa Mitsutake , Hisato Nakazono , Tomoyuki Shiozaki , Takanori Taniguchi , Hisayoshi Yoshizuka , Maiko Sakamoto\",\"doi\":\"10.1016/j.clinph.2024.11.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>Noisy galvanic vestibular stimulation (GVS) using weak random noise waveforms enhances postural stability by modulating vestibular-related neural networks. This study aimed to investigate the neural interference mechanisms of noisy GVS on lateral vestibulospinal tract (LVST) excitability.</div></div><div><h3>Methods</h3><div>Twenty-six healthy volunteers were randomly divided into two groups: balance training combined with noisy GVS and sham GVS. Participants performed 10-minute balance training while standing on a soft foam surface with their eyes closed while adapting to each electrical stimulus. LVST excitability was assessed by measuring the soleus H-reflex following square-wave pulse GVS. Postural stability was measured by assessing the center of foot pressure sway while standing on a foam surface with eyes closed.</div></div><div><h3>Results</h3><div>The noisy GVS group showed significantly increased post-intervention H-reflex amplitude. The sham GVS group showed no significant difference in H-reflex amplitude pre- and post-intervention. The average sway velocity in the noisy and sham GVS groups significantly decreased in the medial–lateral direction of the center of foot pressure.</div></div><div><h3>Conclusions</h3><div>Noisy GVS may enhance LVST excitability and decrease body sway via vestibular system interference during holding upright, which relies heavily on vestibular sensations.</div></div><div><h3>Significance</h3><div>These findings may help understand the neural mechanisms of noisy GVS in neurorehabilitation.</div></div>\",\"PeriodicalId\":10671,\"journal\":{\"name\":\"Clinical Neurophysiology\",\"volume\":\"168 \",\"pages\":\"Pages 153-160\"},\"PeriodicalIF\":3.7000,\"publicationDate\":\"2024-11-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Neurophysiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1388245724003249\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Neurophysiology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1388245724003249","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}

引用次数: 0

摘要

目的：使用弱随机噪声波形的噪声前庭刺激（GVS）可通过调节前庭相关神经网络增强姿势稳定性。本研究旨在探讨噪声前庭刺激对前庭脊髓外侧束（LVST）兴奋性的神经干扰机制：方法：26 名健康志愿者被随机分为两组：平衡训练与高噪音龙胆紫结合组和假龙胆紫组。参与者闭眼站在柔软的泡沫表面上进行 10 分钟的平衡训练，同时适应每种电刺激。通过测量方波脉冲 GVS 后的比目鱼肌 H-反射来评估 LVST 兴奋性。通过评估闭眼站立在泡沫表面时的足底压力中心摇摆来测量姿势稳定性：结果：噪音 GVS 组显示干预后 H 反射振幅明显增加。假龙胆紫组在干预前和干预后的 H- 反射振幅无明显差异。在足底压力中心的内侧-外侧方向上，噪声GVS组和假GVS组的平均摇摆速度明显下降：结论：高噪音 GVS 可增强 LVST 的兴奋性，并在直立时通过前庭系统干扰减少身体摇摆，而身体摇摆在很大程度上依赖于前庭感觉：这些研究结果有助于了解高噪音 GVS 在神经康复中的神经机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Neural interference effects on lateral vestibulospinal tract excitability by noisy galvanic vestibular stimulation

Objective

Noisy galvanic vestibular stimulation (GVS) using weak random noise waveforms enhances postural stability by modulating vestibular-related neural networks. This study aimed to investigate the neural interference mechanisms of noisy GVS on lateral vestibulospinal tract (LVST) excitability.

Methods

Twenty-six healthy volunteers were randomly divided into two groups: balance training combined with noisy GVS and sham GVS. Participants performed 10-minute balance training while standing on a soft foam surface with their eyes closed while adapting to each electrical stimulus. LVST excitability was assessed by measuring the soleus H-reflex following square-wave pulse GVS. Postural stability was measured by assessing the center of foot pressure sway while standing on a foam surface with eyes closed.

Results

The noisy GVS group showed significantly increased post-intervention H-reflex amplitude. The sham GVS group showed no significant difference in H-reflex amplitude pre- and post-intervention. The average sway velocity in the noisy and sham GVS groups significantly decreased in the medial–lateral direction of the center of foot pressure.

Conclusions

Noisy GVS may enhance LVST excitability and decrease body sway via vestibular system interference during holding upright, which relies heavily on vestibular sensations.

Significance

These findings may help understand the neural mechanisms of noisy GVS in neurorehabilitation.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Clinical Neurophysiology 医学-临床神经学

CiteScore

8.70

自引率

6.40%

发文量

932

审稿时长

59 days

期刊介绍： As of January 1999, The journal Electroencephalography and Clinical Neurophysiology, and its two sections Electromyography and Motor Control and Evoked Potentials have amalgamated to become this journal - Clinical Neurophysiology. Clinical Neurophysiology is the official journal of the International Federation of Clinical Neurophysiology, the Brazilian Society of Clinical Neurophysiology, the Czech Society of Clinical Neurophysiology, the Italian Clinical Neurophysiology Society and the International Society of Intraoperative Neurophysiology.The journal is dedicated to fostering research and disseminating information on all aspects of both normal and abnormal functioning of the nervous system. The key aim of the publication is to disseminate scholarly reports on the pathophysiology underlying diseases of the central and peripheral nervous system of human patients. Clinical trials that use neurophysiological measures to document change are encouraged, as are manuscripts reporting data on integrated neuroimaging of central nervous function including, but not limited to, functional MRI, MEG, EEG, PET and other neuroimaging modalities.