消防员职业暴露于空气污染:对慢性阻塞性肺病和哮喘的影响--研究方案。

IF 3.6 3区 医学 Q1 RESPIRATORY SYSTEM
Joana V Barbosa, Pedro T B S Branco, Maria C M Alvim-Ferraz, Fernando G Martins, Sofia I V Sousa
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引用次数: 0

摘要

导言:就接触职业病的影响而言,消防仍然是最危险但研究最少的职业之一。本文报告了一项流行病学研究,旨在缩小在评估森林火灾中的空气污染对消防员的长期影响(即慢性阻塞性肺病(COPD)和哮喘)方面存在的差距:该研究将在森林火灾高发地区(葡萄牙)开展,通过回顾性队列研究(暴露与非暴露),在森林火灾扑救期间使用个人暴露监测器测量空气污染物,分析消防员暴露于火灾排放物的情况。此外,该研究还将根据对有效问卷的回答和医生的体检结果,评估消防员慢性阻塞性肺病和哮喘的患病率、发病率和恶化情况,从而考虑短期和长期影响。根据上述结果,该研究旨在评估森林火灾扑救期间接触和吸入空气污染物的剂量对上述慢性疾病发展的影响。参与研究的人数大约不会少于 186 人,以保证 80% 的研究力量(在 5%的水平上具有显著性):该研究已获得圣若昂大学中心医院伦理委员会的批准。研究结果将在国际和国内期刊及会议上发表,以便向科学界传播所取得的成果。此外,还将向利益攸关方和决策者传播最新数据,帮助他们决定是否启动官方控制措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Firefighters' occupational exposure to air pollution: impact on COPD and asthma-study protocol.

Introduction: Firefighting continues to be among the most hazardous yet least studied occupations in terms of the impact of exposure to occupational disease. In particular, firefighters are at increased risk of adverse health effects due to exposure to significant levels of potentially harmful substances, namely carbon monoxide, particulate matter and formaldehyde, during their professional duties.This paper reports an epidemiologic study aiming to reduce the gaps in assessing the long-term effects of air pollution exposure to forest fires' combat on firefighters, namely regarding chronic obstructive pulmonary Disease (COPD) and asthma.

Methods and analysis: Based on the implementation in an area with high forest fires (in Portugal), the study will analyse firefighters' exposure to fire emissions by measuring air pollutants with personal exposure monitors during forest fire combat through a retrospective cohort study (exposed vs non-exposed). Moreover, based on answers to validated questionnaires and medical examinations to be performed by medical doctors, the study will assess the prevalence, incidence and exacerbation of COPD and asthma in firefighters, thus considering both short-term and long-term effects. Based on the results above referred, the study aims to evaluate the impact of exposure and inhalation dose of air pollutants during forest fires' combat on the development of the above-referred chronic diseases. The approximate number of participants in the study will never be less than 186, guaranteeing 80% of study power (significant at a 5% level).

Ethics and dissemination: The study has been approved by the Ethical Committee of Centro Hospitalar Universitário São João. The results will be published in international and national journals and conferences, allowing the results obtained to be communicated to the scientific community. Moreover, up-to-date data will be disseminated to stakeholders and decision-makers to help them decide on triggering official control measures.

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来源期刊
BMJ Open Respiratory Research
BMJ Open Respiratory Research RESPIRATORY SYSTEM-
CiteScore
6.60
自引率
2.40%
发文量
95
审稿时长
12 weeks
期刊介绍: BMJ Open Respiratory Research is a peer-reviewed, open access journal publishing respiratory and critical care medicine. It is the sister journal to Thorax and co-owned by the British Thoracic Society and BMJ. The journal focuses on robustness of methodology and scientific rigour with less emphasis on novelty or perceived impact. BMJ Open Respiratory Research operates a rapid review process, with continuous publication online, ensuring timely, up-to-date research is available worldwide. The journal publishes review articles and all research study types: Basic science including laboratory based experiments and animal models, Pilot studies or proof of concept, Observational studies, Study protocols, Registries, Clinical trials from phase I to multicentre randomised clinical trials, Systematic reviews and meta-analyses.
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