Daniel J Levendowski, Lana M Chahine, Simon J G Lewis, Thomas J Finstuen, Andrea Galbiati, Chris Berka, Sherri Mosovsky, Hersh Parikh, Jack Anderson, Christine M Walsh, Joyce K Lee-Iannotti, Thomas C Neylan, Luigi Ferini Strambi, Bradley F Boeve, Erik K St Louis
{"title":"利用实验室和家庭记录验证无失眠的快速眼动睡眠自动检测。","authors":"Daniel J Levendowski, Lana M Chahine, Simon J G Lewis, Thomas J Finstuen, Andrea Galbiati, Chris Berka, Sherri Mosovsky, Hersh Parikh, Jack Anderson, Christine M Walsh, Joyce K Lee-Iannotti, Thomas C Neylan, Luigi Ferini Strambi, Bradley F Boeve, Erik K St Louis","doi":"10.5664/jcsm.11488","DOIUrl":null,"url":null,"abstract":"<p><strong>Study objectives: </strong>To evaluate the concordance between visual scoring and automated detection of REM sleep without atonia (RSWA) and the validity and reliability of in-home automated-RSWA detection in REM sleep behavior disorder (RBD) patients and a control group (CG).</p><p><strong>Methods: </strong>Sleep Profiler signals were acquired during simultaneous in-laboratory polysomnography in 24 isolated RBD patients. Chin and arm RSWA measures visually scored by an expert sleep technologist were compared to algorithms designed to automate RSWA detection. In a second cohort, the accuracy of automated-RSWA detection for discriminating between RBD and CG (n = 21 and 42, respectively) was assessed in multi-night in-home recordings.</p><p><strong>Results: </strong>For the in-laboratory studies, agreement between visual and auto-scored RSWA from the chin and arm were excellent, with intra-class correlations of 0.89 and 0.95, respectively, and substantial, based on Kappa scores of 0.68 and 0.74, respectively. For classification of iRBD patients versus controls, specificities derived from auto-detected RSWA densities obtained from in-home recordings were 0.88 for the chin, 0.93 for the arm, and 0.90 for the chin or arm, while the sensitivities were 0.81, 0.81 and 0.86, respectively. The night-to-night consistencies of the respective auto-detected RSWA densities were good based on intra-class correlations of 0.81, 0.79 and 0.84, however some night-to-night disagreements in abnormal RSWA detection were observed.</p><p><strong>Conclusions: </strong>When compared to expert visual RSWA scoring, automated RSWA detection demonstrates promise for detection of RBD. The night-to-night reliability of chin- and arm-RSWA densities acquired in-home were equivalent.</p>","PeriodicalId":50233,"journal":{"name":"Journal of Clinical Sleep Medicine","volume":" ","pages":""},"PeriodicalIF":3.5000,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Validation of automated detection of REM sleep without atonia using in-laboratory and in-home recordings.\",\"authors\":\"Daniel J Levendowski, Lana M Chahine, Simon J G Lewis, Thomas J Finstuen, Andrea Galbiati, Chris Berka, Sherri Mosovsky, Hersh Parikh, Jack Anderson, Christine M Walsh, Joyce K Lee-Iannotti, Thomas C Neylan, Luigi Ferini Strambi, Bradley F Boeve, Erik K St Louis\",\"doi\":\"10.5664/jcsm.11488\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Study objectives: </strong>To evaluate the concordance between visual scoring and automated detection of REM sleep without atonia (RSWA) and the validity and reliability of in-home automated-RSWA detection in REM sleep behavior disorder (RBD) patients and a control group (CG).</p><p><strong>Methods: </strong>Sleep Profiler signals were acquired during simultaneous in-laboratory polysomnography in 24 isolated RBD patients. Chin and arm RSWA measures visually scored by an expert sleep technologist were compared to algorithms designed to automate RSWA detection. In a second cohort, the accuracy of automated-RSWA detection for discriminating between RBD and CG (n = 21 and 42, respectively) was assessed in multi-night in-home recordings.</p><p><strong>Results: </strong>For the in-laboratory studies, agreement between visual and auto-scored RSWA from the chin and arm were excellent, with intra-class correlations of 0.89 and 0.95, respectively, and substantial, based on Kappa scores of 0.68 and 0.74, respectively. For classification of iRBD patients versus controls, specificities derived from auto-detected RSWA densities obtained from in-home recordings were 0.88 for the chin, 0.93 for the arm, and 0.90 for the chin or arm, while the sensitivities were 0.81, 0.81 and 0.86, respectively. The night-to-night consistencies of the respective auto-detected RSWA densities were good based on intra-class correlations of 0.81, 0.79 and 0.84, however some night-to-night disagreements in abnormal RSWA detection were observed.</p><p><strong>Conclusions: </strong>When compared to expert visual RSWA scoring, automated RSWA detection demonstrates promise for detection of RBD. The night-to-night reliability of chin- and arm-RSWA densities acquired in-home were equivalent.</p>\",\"PeriodicalId\":50233,\"journal\":{\"name\":\"Journal of Clinical Sleep Medicine\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2024-11-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Clinical Sleep Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.5664/jcsm.11488\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Sleep Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5664/jcsm.11488","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Validation of automated detection of REM sleep without atonia using in-laboratory and in-home recordings.
Study objectives: To evaluate the concordance between visual scoring and automated detection of REM sleep without atonia (RSWA) and the validity and reliability of in-home automated-RSWA detection in REM sleep behavior disorder (RBD) patients and a control group (CG).
Methods: Sleep Profiler signals were acquired during simultaneous in-laboratory polysomnography in 24 isolated RBD patients. Chin and arm RSWA measures visually scored by an expert sleep technologist were compared to algorithms designed to automate RSWA detection. In a second cohort, the accuracy of automated-RSWA detection for discriminating between RBD and CG (n = 21 and 42, respectively) was assessed in multi-night in-home recordings.
Results: For the in-laboratory studies, agreement between visual and auto-scored RSWA from the chin and arm were excellent, with intra-class correlations of 0.89 and 0.95, respectively, and substantial, based on Kappa scores of 0.68 and 0.74, respectively. For classification of iRBD patients versus controls, specificities derived from auto-detected RSWA densities obtained from in-home recordings were 0.88 for the chin, 0.93 for the arm, and 0.90 for the chin or arm, while the sensitivities were 0.81, 0.81 and 0.86, respectively. The night-to-night consistencies of the respective auto-detected RSWA densities were good based on intra-class correlations of 0.81, 0.79 and 0.84, however some night-to-night disagreements in abnormal RSWA detection were observed.
Conclusions: When compared to expert visual RSWA scoring, automated RSWA detection demonstrates promise for detection of RBD. The night-to-night reliability of chin- and arm-RSWA densities acquired in-home were equivalent.
期刊介绍:
Journal of Clinical Sleep Medicine focuses on clinical sleep medicine. Its emphasis is publication of papers with direct applicability and/or relevance to the clinical practice of sleep medicine. This includes clinical trials, clinical reviews, clinical commentary and debate, medical economic/practice perspectives, case series and novel/interesting case reports. In addition, the journal will publish proceedings from conferences, workshops and symposia sponsored by the American Academy of Sleep Medicine or other organizations related to improving the practice of sleep medicine.