产前多种维生素和矿物质中部分营养素和潜在污染物的含量：一项观察研究。

IF 6.5 1区医学 Q1 NUTRITION & DIETETICS

American Journal of Clinical Nutrition Pub Date : 2024-11-19 DOI:10.1016/j.ajcnut.2024.11.014

Laura M Borgelt, Michael Armstrong, Stephen Brindley, Jared M Brown, Nichole Reisdorph, Carol A Stamm

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引用次数: 0

摘要

背景：消费者对产前多种维生素和矿物质（PMVMs）的依赖日益增加，这凸显了确保其质量和安全性的重要性。孕期摄入充足的胆碱和碘对胎儿的发育至关重要，然而，产前多种维生素和矿物质产品的标示含量与实际含量之间的差异会对健康造成重大风险。此外，有毒重金属（如砷、铅和镉）的潜在存在也引起了人们对潜在不良健康影响的担忧：评估非处方和处方 PMVM 的胆碱和碘含量以及砷、铅和镉含量：这项观察性研究对网上零售商和当地零售药店的非处方和处方 PMVM 产品进行了方便抽样评估。使用液相色谱质谱法分析了产品中的胆碱含量，并使用电感耦合等离子体质谱法分析了产品中的碘、砷、铅和镉含量。胆碱和碘的实际含量与报告的标签含量进行比较，污染物含量与美国药典 (USP) 标准进行比较：共分析了 32 种非处方药和 15 种处方药 PMVM 产品。12/47（25.6%）种产品报告了胆碱含量，其中5（41.7%）种产品的胆碱含量在标称含量的20%以内，2（16.7%）种产品的胆碱含量超出标称含量20%以上，5（41.7%）种产品的胆碱含量低于标称含量20%以上。25/47（53.2%）个产品报告了碘含量，其中 4（16.0%）个产品的碘含量在索赔量的 20% 以内，20（80.0%）个产品的碘含量低于索赔量 20%以上，1（4.0%）个产品的碘含量高于索赔量 20%以上。在7种（14.9%）、2种（4.3%）和13种（27.7%）永磁真空吸塑中发现的砷、铅和镉含量超过了USP纯度限值：结论：目前的 PMVM 标签具有误导性，可能因遗漏或不准确的必需营养素含量和重金属含量而对孕妇和胎儿造成伤害。需要进行监管，食品和药物管理局需要足够的权力和人员来监督这些膳食补充剂。

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TEMPORARY REMOVAL: Content of selected nutrients and potential contaminants in prenatal multivitamins and minerals: an observational study.

The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies/article-withdrawal.

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来源期刊

American Journal of Clinical Nutrition 医学-营养学

CiteScore

12.40

自引率

4.20%

发文量

332

审稿时长

38 days

期刊介绍： American Journal of Clinical Nutrition is recognized as the most highly rated peer-reviewed, primary research journal in nutrition and dietetics.It focuses on publishing the latest research on various topics in nutrition, including but not limited to obesity, vitamins and minerals, nutrition and disease, and energy metabolism. Purpose: The purpose of AJCN is to: Publish original research studies relevant to human and clinical nutrition. Consider well-controlled clinical studies describing scientific mechanisms, efficacy, and safety of dietary interventions in the context of disease prevention or health benefits. Encourage public health and epidemiologic studies relevant to human nutrition. Promote innovative investigations of nutritional questions employing epigenetic, genomic, proteomic, and metabolomic approaches. Include solicited editorials, book reviews, solicited or unsolicited review articles, invited controversy position papers, and letters to the Editor related to prior AJCN articles. Peer Review Process: All submitted material with scientific content undergoes peer review by the Editors or their designees before acceptance for publication.