探索近视眼倾斜视盘的光学相干断层成像参数。

IF 4.1 1区 医学 Q1 OPHTHALMOLOGY
Yu Qiao Zhang, Xiu Juan Zhang, Ru Yue Shen, Yuzhou Zhang, Fang Yao Tang, Simon K H Szeto, Danny Siu-Chun Ng, Ka Wai Kam, Alvin L Young, Li Jia Chen, Chi Pui Pang, Clement C Tham, Jason C Yam, Poemen P Chan
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引用次数: 0

摘要

背景:目的:研究视盘扭转(ODT)、视盘水平倾斜角(HDT)和椭圆度指数(OI)对健康近视眼不同视网膜神经纤维层(RNFL)和神经节细胞-内丛状层(GCIPL)节段的影响:根据眼底照片测量 ODT 和 OI。通过扫源光学相干断层扫描(SS-OCT)测量 HDT 角、毛周 RNFL 和黄斑 GCIPL。在对年龄和轴长(AL)进行调整后,评估了视盘形态与 RNFL/GCIPL 厚度之间的关联:在 284 名参与者的 530 只健康近视眼中(平均年龄:41.7 岁,平均球面等值:- 7.70 D,平均轴长:26.6 mm),有 335 只眼睛(63.2%)患有颞侧视盘扭转(颞侧组),195 只眼睛(36.8%)患有鼻侧视盘扭转(鼻侧组)。对于鼻腔组,较大的 OI 与较薄的上鼻腔 GCIPL(β = - 7.465 到 - 6.972,P = 0.024)和颞部 RNFL 扇区(β = - 49.596 到 - 27.748,P ≤ 0.014)相关。对于颞叶组,较大的 OI 与较薄的鼻上部(β = - 50.255 至 - 22.093,P ≤ 0.006)和较厚的颞叶 RNFL 扇区(β = 29.015 至 56.890,P ≤ 0.003)相关。此外,HDT 角度越大,上鼻腔 RNFL 区段越薄(β = - 0.559 至 - 0.242,P≤ 0.036),上颞上 GCIPL 区段越薄(β = - 0.084 至 - 0.069,P≤ 0.037):结论:视盘扭转方向与不同 RNFL 和 GCIPL 区段的测量有关,与 AL 和年龄无关。在构建近视标准数据库时应考虑这些因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exploring optical coherence tomography parameters in eyes with myopic tilted disc.

Background: To investigate the impact of optic disc torsion (ODT), horizontal disc tilt (HDT) angle, and ovality index (OI) on different retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL) segments in healthy myopic eyes.

Methods: ODT and OI were measured from fundus photographs. HDT angle, peripapillary RNFL, and macular GCIPL were measured by swept-source optical coherence tomography (SS-OCT). The association between optic disc morphology and the RNFL/GCIPL thickness were evaluated, with age and axial length (AL) adjusted.

Results: Among 530 healthy myopic eyes of 284 participants (mean age: 41.7 years, mean spherical equivalent: - 7.70 D, and mean AL: 26.6 mm), 335 eyes (63.2%) had temporal disc torsion (temporal group) and 195 eyes (36.8%) had nasal disc torsion (nasal group). For the nasal group, a larger OI was associated with thinner superior-to-superonasal GCIPL (β = - 7.465 to - 6.972, both P = 0.024) and temporal RNFL sectors (β = - 49.596 to - 27.748, P ≤ 0.014). For the temporal group, a larger OI was associated with thinner superior-to-nasal (β = - 50.255 to - 22.093, P ≤ 0.006) and thicker temporal RNFL sectors (β = 29.015 to 56.890, P ≤ 0.003). Additionally, a larger HDT angle was associated with thinner superior-to-nasal RNFL sectors (β = - 0.559 to - 0.242, P ≤ 0.036) and thinner superior-to-superotemporal GCIPL sectors (β = - 0.084 to - 0.069, P ≤ 0.037).

Conclusions: The optic disc tortional direction was associated with the measurement of different RNFL and GCIPL sectors independent of the AL and age. These should be considered when constructing a myopic normative database.

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来源期刊
Eye and Vision
Eye and Vision OPHTHALMOLOGY-
CiteScore
8.60
自引率
2.40%
发文量
89
审稿时长
15 weeks
期刊介绍: Eye and Vision is an open access, peer-reviewed journal for ophthalmologists and visual science specialists. It welcomes research articles, reviews, methodologies, commentaries, case reports, perspectives and short reports encompassing all aspects of eye and vision. Topics of interest include but are not limited to: current developments of theoretical, experimental and clinical investigations in ophthalmology, optometry and vision science which focus on novel and high-impact findings on central issues pertaining to biology, pathophysiology and etiology of eye diseases as well as advances in diagnostic techniques, surgical treatment, instrument updates, the latest drug findings, results of clinical trials and research findings. It aims to provide ophthalmologists and visual science specialists with the latest developments in theoretical, experimental and clinical investigations in eye and vision.
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