生物纳米粒子作为治疗胃溃疡的更安全替代品:绿色合成方法、毒性及其控制炎症功效的最新进展。

IF 3.4 3区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
Susmita Yadav, Suraj N Mali, Anima Pandey
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引用次数: 0

摘要

消化性溃疡约占全球人口的 10%,可由压力、饮酒、吸烟、非甾体抗炎药、幽门螺旋杆菌感染和遗传易感性等因素引起。以植物为基础的药物在治疗消化性溃疡等方面的潜力正日益得到认可。生物合成纳米粒子(NPs)的绿色化学方法为传统化学技术提供了一种可持续的替代方法。这些纳米粒子,尤其是用植物提取物合成的金属 NPs 和金属氧化物,具有良好的抗溃疡特性。本综述重点介绍了 2000 年至 2024 年期间有关使用绿色合成纳米粒子及其在消化性溃疡治疗中的作用的研究,重点关注其治疗机制和潜在益处。为此,我们在 PubMed、Scopus、Science Direct、Cochrane 数据库和 Google Scholar 中对已发表的研究和综述文章进行了电子检索。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Biogenic Nanoparticles as Safer Alternatives for Gastric Ulcers: An Update on Green Synthesis Methods, Toxicity, and Their Efficacy in Controlling Inflammation.

Peptic ulcers, affecting approximately 10% of the global population, can result from factors such as stress, alcohol use, smoking, NSAIDs, Helicobacter pylori infection, and genetic predisposition. Plant-based medicines are gaining recognition for their therapeutic potential, including in the treatment of peptic ulcers. Green chemistry methods for the biological synthesis of nanoparticles (NPs) provide a sustainable alternative to traditional chemical techniques. These nanoparticles, particularly metallic NPs and metal oxides synthesized from plant extracts, offer promising anti-ulcer properties. This review highlights research from 2000 to 2024 on the use of green-synthesized nanoparticles and their role in peptic ulcer treatment, focusing on their therapeutic mechanisms and potential benefits. For this purpose, an electronic search of published research and review articles was conducted in PubMed, Scopus, Science Direct, Cochrane databases, and Google Scholar.

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来源期刊
Biological Trace Element Research
Biological Trace Element Research 生物-内分泌学与代谢
CiteScore
8.70
自引率
10.30%
发文量
459
审稿时长
2 months
期刊介绍: Biological Trace Element Research provides a much-needed central forum for the emergent, interdisciplinary field of research on the biological, environmental, and biomedical roles of trace elements. Rather than confine itself to biochemistry, the journal emphasizes the integrative aspects of trace metal research in all appropriate fields, publishing human and animal nutritional studies devoted to the fundamental chemistry and biochemistry at issue as well as to the elucidation of the relevant aspects of preventive medicine, epidemiology, clinical chemistry, agriculture, endocrinology, animal science, pharmacology, microbiology, toxicology, virology, marine biology, sensory physiology, developmental biology, and related fields.
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