探索外泌体在皮肤病学中的应用。

IF 2.6 4区 医学 Q2 DERMATOLOGY
Taciana Dal'Forno-Dini, Martina Souilljee Birck, Marco Rocha, Edileia Bagatin
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引用次数: 0

摘要

外泌体是人和动物体内一些细胞分泌的细胞外纳米囊泡。外泌体由脂质膜和包裹的蛋白质组成,含有蛋白质、DNA、RNA、转录因子和代谢物等生物活性物质。外泌体发现于 20 世纪 80 年代,在细胞间通信和免疫功能中发挥着重要作用。外泌体的大小、含量和功能因细胞来源而异。外泌体在治疗疤痕、皮肤再生、毛发再生和其他皮肤病方面的潜在应用引起了皮肤病学领域的兴趣。不过,还需要进一步的临床研究来证明其有效性和安全性。由于一些国家尚未完全批准在化妆品和医疗中使用外泌体,因此还需要考虑监管问题。此外,在临床使用外泌体之前,必须了解与使用外泌体相关的风险和副作用。外泌体虽然前景广阔,但要充分发掘其在医学和皮肤病学方面的潜力,还需要更多的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exploring the reality of exosomes in dermatology.

Exosomes are extracellular nanovesicles secreted by several cells in the human and animal body. Consisting of a lipid membrane and encapsulated proteins, they contain biologically active substances such as proteins, DNA, RNA, transcription factors, and metabolites. Discovered in the 1980s, exosomes play an important role in cell-to-cell communication and immune function. They vary in size, content, and function depending on the cell of origin. Exosomes have attracted interest in the field of Dermatology due to their potential applications in the treatment of scars, skin rejuvenation, hair regeneration, and other dermatological conditions. However, further clinical studies are needed to prove their efficacy and safety. Regulatory issues also need to be considered, as the use of exosomes in cosmetics and medical treatments is not yet fully approved in some countries. Moreover, it is important to understand the risks and side effects associated with the use of exosomes before their clinical use. Although promising, more research is needed to explore the full potential of exosomes in Medicine and Dermatology.

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来源期刊
CiteScore
2.40
自引率
0.00%
发文量
184
审稿时长
32 days
期刊介绍: The journal is published bimonthly and is devoted to the dissemination of original, unpublished technical-scientific study, resulting from research or reviews of dermatological topics and related matters. Exchanges with other publications may be accepted.
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