在一名巴西骨髓捐献者中鉴定出新型 HLA-DPA1*01:214 等位基因

IF 5.9 4区医学 Q2 CELL BIOLOGY

HLA Pub Date : 2024-11-20 DOI:10.1111/tan.15774

Ana Paula Sokolowski de Lima, Rafael Formenton Cita, Fernanda Pelisson Massi, Bruna Karina Banin Hirata, Jeane Eliete Laguila Visentainer

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引用次数: 0

摘要

单核苷酸多态性将苯丙氨酸变为亮氨酸，从而将 HLA-DPA1*01:214 与 HLA-DPA1*01:03:01:01 区分开来。

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Identification of the Novel HLA-DPA1*01:214 Allele in a Brazilian Bone Marrow Donor

A single nucleotide polymorphism, changing Phenylalanine to Leucine, differentiates HLA-DPA1*01:214 from HLA-DPA1*01:03:01:01.

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来源期刊

HLA Immunology and Microbiology-Immunology

CiteScore

3.00

自引率

28.80%

发文量

368

期刊介绍： HLA, the journal, publishes articles on various aspects of immunogenetics. These include the immunogenetics of cell surface antigens, the ontogeny and phylogeny of the immune system, the immunogenetics of cell interactions, the functional aspects of cell surface molecules and their natural ligands, and the role of tissue antigens in immune reactions. Additionally, the journal covers experimental and clinical transplantation, the relationships between normal tissue antigens and tumor-associated antigens, the genetic control of immune response and disease susceptibility, and the biochemistry and molecular biology of alloantigens and leukocyte differentiation. Manuscripts on molecules expressed on lymphoid cells, myeloid cells, platelets, and non-lineage-restricted antigens are welcomed. Lastly, the journal focuses on the immunogenetics of histocompatibility antigens in both humans and experimental animals, including their tissue distribution, regulation, and expression in normal and malignant cells, as well as the use of antigens as markers for disease.