单锅合成取代的苯并咪唑-嘧啶衍生物

IF 0.9 4区化学 Q4 CHEMISTRY, MULTIDISCIPLINARY

Russian Journal of General Chemistry Pub Date : 2024-11-19 DOI:10.1134/S1070363224100128

F. Abboub, M. Amari, M. Fodili, Pascal Hoffmann

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引用次数: 0

摘要

这项工作的主要目的是利用各种醇类溶剂，通过缩合 2-氨基苯并咪唑和前体 4-羟基-6-甲基吡喃-2-酮，合成苯并[4,5]咪唑并[1,2-a]嘧啶杂化物的多环分子。利用各种光谱方法（核磁共振、质谱、红外光谱和碳氢化合物）对合成的化合物进行了结构表征。详细的反应机理解释了所获结构的形成。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

One-Pot Synthesis of Substituted Benzimidazole-Pyrimidine Derivatives

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One-Pot Synthesis of Substituted Benzimidazole-Pyrimidine Derivatives

The main objective of this work is the synthesis of polycyclic molecules of benzo[4,5]imidazo[1,2-a]pyrimidine hybrids by condensation of 2-aminobenzimidazole with the precursor 4-hydroxy-6-methylpyran-2-one utilizing various alcoholic solvents. Structural characterization of the synthesized compounds was conducted using diverse spectroscopic methods (NMR, MS, IR, and CHN). The formation of the obtained structures is explained by a detailed reaction mechanism.

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来源期刊

Russian Journal of General Chemistry 化学-化学综合

CiteScore

1.40

自引率

22.20%

发文量

252

审稿时长

2-4 weeks

期刊介绍： Russian Journal of General Chemistry is a journal that covers many problems that are of general interest to the whole community of chemists. The journal is the successor to Russia’s first chemical journal, Zhurnal Russkogo Khimicheskogo Obshchestva (Journal of the Russian Chemical Society ) founded in 1869 to cover all aspects of chemistry. Now the journal is focused on the interdisciplinary areas of chemistry (organometallics, organometalloids, organoinorganic complexes, mechanochemistry, nanochemistry, etc.), new achievements and long-term results in the field. The journal publishes reviews, current scientific papers, letters to the editor, and discussion papers.