纳米酶:牙科抗菌应用的理想解决方案

IF 3.9 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY
RSC Advances Pub Date : 2024-11-20 DOI:10.1039/D4RA07303G
Lipeng Liu, Yaoyuan Zhang, Tianjuan Ju, Xutao Chen, Xinwei Li and Li-an Wu
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引用次数: 0

摘要

牙科疾病对全球公共卫生构成重大挑战,数百万人因微生物引起的炎症而病情加重。传统的天然酶尽管具有抗菌消炎能力,但却受到操作稳定性和环境敏感性的限制。本综述探讨了纳米酶--由纳米材料制成的人造酶--的革命性领域,这种酶具有更高的稳定性、成本效益和易改性。我们讨论了纳米酶自 2007 年首次被认识以来的发展历程,强调了它们的酶模拟能力和在牙科医学中的应用,特别是在龋齿、牙髓炎、牙周炎和种植体周围炎方面的应用。本文对纳米酶的分类、机制和新兴应用进行了全面分析,揭示了纳米酶彻底改变牙科抗菌治疗的潜力,并探讨了纳米酶目前面临的挑战和未来的发展前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Nanozymes: a promising solution for dental antibacterial applications

Nanozymes: a promising solution for dental antibacterial applications

Dental diseases pose significant public health challenges globally, affecting millions with conditions exacerbated by microbial-induced inflammation. Traditional natural enzymes, despite their antibacterial and anti-inflammatory capabilities, are limited by operational stability and environmental sensitivity. This review explores the revolutionary realm of nanozyme-artificial enzymes made from nanomaterials-which offer enhanced stability, cost-effectiveness, and ease of modification. We discuss the advent of nanozymes since their first recognition in 2007, emphasizing their enzyme-mimicking capabilities and applications in dental medicine, particularly for dental caries, pulpitis, periodontitis and peri-implantitis. This paper presents a comprehensive analysis of nanozymes' classification, mechanisms, and emerging applications, shedding light on their potential to revolutionize dental antibacterial treatments and addressing current challenges and future perspectives in their development.

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来源期刊
RSC Advances
RSC Advances chemical sciences-
CiteScore
7.50
自引率
2.60%
发文量
3116
审稿时长
1.6 months
期刊介绍: An international, peer-reviewed journal covering all of the chemical sciences, including multidisciplinary and emerging areas. RSC Advances is a gold open access journal allowing researchers free access to research articles, and offering an affordable open access publishing option for authors around the world.
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