在意大利分离到的携带 blaNDM-5 和 blaOXA-48 的肺炎克雷伯氏菌临床菌株的分离和基因组特征。

IF 1.5 4区医学 Q4 MICROBIOLOGY

New Microbiologica Pub Date : 2024-11-01

Stefano Amadesi, Erica Diani, Annarita Mazzariol, Davide Gibellini, Paolo Gaibani

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引用次数: 0

摘要

产碳青霉烯酶肠杆菌（CPE）是全球公共卫生面临的一个新威胁，也是临床医生面临的一个严重问题，因为可用的治疗方案有限。最近，世界各地通过描述不同的抗菌机制来描述 CPE 的出现。在此，我们描述了在意大利分离到的一种携带双碳酸烯酵素酶的 CPE，并对其基因组中的抗菌耐药基因、毒力因子和噬菌体区域进行了深入分析。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

Isolation and genome characterization of a Klebsiella pneumoniae clinical strain carrying blaNDM-5 and blaOXA-48 isolated in Italy.

Carbapenemase-producing Enterobacteriales (CPE) represent an emerging threat for global public health and a serious problem for clinicians due to the limited available treatment options. The emergence of CPE has been recently described worldwide by describing different antimicrobial mechanisms. Here, we describe a CPE carrying dual-carbapenemase isolated in Italy and we provide a deep characterization of the antimicrobial resistance genes, virulence-factors and prophage regions within the genome.

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来源期刊

New Microbiologica 生物-微生物学

CiteScore

2.20

自引率

5.60%

发文量

审稿时长

6-12 weeks

期刊介绍： The publication, diffusion and furtherance of research and study on all aspects of basic and clinical Microbiology and related fields are the chief aims of the journal.