肺炎支原体肺炎患儿混合感染的流行病学特征和相关风险因素。

IF 1.5 4区 医学 Q4 MICROBIOLOGY
New Microbiologica Pub Date : 2024-11-01
Wenli Lv, Chunyan Guo, Guofeng Lv, Xueqin Xi
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引用次数: 0

摘要

肺炎支原体感染是肺炎的一种表现形式,可同时合并多种细菌菌群感染。本研究探讨了支原体肺炎(MP)患儿混合感染的流行病学特征和相关风险因素。研究共招募了 462 名支原体肺炎患儿,将其分为单纯感染组和混合感染组。混合感染组又分为细菌组、病毒组和衣原体组。收集临床数据以探讨流行病学特征,并通过逻辑回归分析相关因素。混合感染组的合并感染率最高(50.27%)。1 岁以下儿童的细菌合并感染率最高(40.95%)。1-5 岁和 5 岁以上儿童的病毒合并感染率最高(39.53%、51.51%)。9 月至 11 月的患者更容易感染病毒(52.73%),12 月至 2 月的患者更容易感染细菌(52.73%)。并发病毒、细菌和衣原体感染的独立危险因素分别是肺外并发症、发烧超过 10 天、白细胞计数(WBC)高和年龄。结论:分析MP患儿混合感染的流行病学特征和危险因素,可指导临床医生制定更合理的诊疗方案,减少混合感染的发生,提高治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epidemiological characteristics and related risk factors of mixed infection in children with mycoplasma pneumoniae pneumonia.

Mycoplasma pneumoniae infection is a manifestation of pneumonia, which can be combined with multiple bacterial flora infection at the same time. This study explored the epidemiological characteristics and related risk factors of mixed infection in children with mycoplasma pneumonia (MP). 462 children with MP were enrolled and divided into simple infection and mixed infection groups. The mixed infection group was further divided into concurrent bacteria, virus, and chlamydia groups. Clinical data were collected to explore the epidemiological characteristics, and the related factors were analyzed by logistic regression. The co-infection rate was the highest in the mixed infection group (50.27%). Children under 1 year of age had the highest bacterial co-infection rate (40.95%). Children aged 1-5 years and >5 years had the highest viral co-infection rate (39.53%, 51.51%). Patients were more likely to be infected with virus from September to November (52.73%), and patients were more likely to be infected with bacteria from December to February (52.73%). The independent risk factors for concurrent viral, bacterial, and chlamydia infections were extrapulmonary complications, fever >10 days, high white blood cell count (WBC), and age, respectively. Conclusion: analysis of the epidemiological characteristics and risk factors of mixed infection in children with MP can provide guidance for clinicians to formulate a more reasonable diagnosis and treatment plan, reduce the occurrence of mixed infection, and improve the treatment effect.

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来源期刊
New Microbiologica
New Microbiologica 生物-微生物学
CiteScore
2.20
自引率
5.60%
发文量
40
审稿时长
6-12 weeks
期刊介绍: The publication, diffusion and furtherance of research and study on all aspects of basic and clinical Microbiology and related fields are the chief aims of the journal.
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