{"title":"基于炎症的营养工具(格拉斯哥预后评分)与血液肿瘤患者住院时间的关系。","authors":"Anqi Song, Beiwen Ni, Molian Tang, Yiquan Zhou, Xiaomin Zhang, Zhiqi Chen, Lijing Shen, Renying Xu","doi":"10.1007/s00520-024-09021-0","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>This is a retrospective study to identify if Glasgow Prognostic Score (GPS) is associated with length of hospital stay (LOS) in haematological cancer.</p><p><strong>Methods: </strong>The participants were adult inpatients at a single centre in between 2018 and 2022. Serum levels of CRP and albumin were measured at admission. GPS was calculated as follows: point \"0\" as CRP < 10 mg/L and albumin ≥ 35 g/L; point \"2\" as CRP ≥ 10 mg/L and albumin < 35 g/L; point \"1\" as either CRP ≥ 10 mg/L or albumin < 35 g/L. Patients with point \"0\" were classified as low risk whilst point \"2\" as high risk. LOS was defined as the interval between the admission and discharge date.</p><p><strong>Results: </strong>As a result, the average age was 59.6 ± 12.6 years and the average LOS was 6.0 days (IQR = 2 days, 11 days). Of 1621 patients, 8.8% of them were high risk. GPS was associated with LOS (β = 2.7 days; 95% CI = 0.8 days, 4.6 days; p trend < 0.001) after full adjustment. Each point of GPS was associated with 1.9 days (95% CI = 1.4 days, 2.4 days) longer in LOS with full adjustment. The association was more prominent in younger patients (< 65 years), patients with leukaemia and myelodysplastic syndrome, and those with normal body weight status (18.5-24 kg/m<sup>2</sup>), compared with their counterparts.</p><p><strong>Conclusion: </strong>GPS was associated with LOS in Chinese patients with haematological cancer, indicating GPS could be a useful tool to predict outcome.</p>","PeriodicalId":22046,"journal":{"name":"Supportive Care in Cancer","volume":"32 12","pages":"804"},"PeriodicalIF":2.8000,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The association between an inflammation-based nutritional tool (Glasgow Prognostic Score) and length of hospital stay in patients with haematological cancer.\",\"authors\":\"Anqi Song, Beiwen Ni, Molian Tang, Yiquan Zhou, Xiaomin Zhang, Zhiqi Chen, Lijing Shen, Renying Xu\",\"doi\":\"10.1007/s00520-024-09021-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>This is a retrospective study to identify if Glasgow Prognostic Score (GPS) is associated with length of hospital stay (LOS) in haematological cancer.</p><p><strong>Methods: </strong>The participants were adult inpatients at a single centre in between 2018 and 2022. Serum levels of CRP and albumin were measured at admission. GPS was calculated as follows: point \\\"0\\\" as CRP < 10 mg/L and albumin ≥ 35 g/L; point \\\"2\\\" as CRP ≥ 10 mg/L and albumin < 35 g/L; point \\\"1\\\" as either CRP ≥ 10 mg/L or albumin < 35 g/L. Patients with point \\\"0\\\" were classified as low risk whilst point \\\"2\\\" as high risk. LOS was defined as the interval between the admission and discharge date.</p><p><strong>Results: </strong>As a result, the average age was 59.6 ± 12.6 years and the average LOS was 6.0 days (IQR = 2 days, 11 days). Of 1621 patients, 8.8% of them were high risk. GPS was associated with LOS (β = 2.7 days; 95% CI = 0.8 days, 4.6 days; p trend < 0.001) after full adjustment. Each point of GPS was associated with 1.9 days (95% CI = 1.4 days, 2.4 days) longer in LOS with full adjustment. The association was more prominent in younger patients (< 65 years), patients with leukaemia and myelodysplastic syndrome, and those with normal body weight status (18.5-24 kg/m<sup>2</sup>), compared with their counterparts.</p><p><strong>Conclusion: </strong>GPS was associated with LOS in Chinese patients with haematological cancer, indicating GPS could be a useful tool to predict outcome.</p>\",\"PeriodicalId\":22046,\"journal\":{\"name\":\"Supportive Care in Cancer\",\"volume\":\"32 12\",\"pages\":\"804\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2024-11-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Supportive Care in Cancer\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00520-024-09021-0\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"HEALTH CARE SCIENCES & SERVICES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Supportive Care in Cancer","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00520-024-09021-0","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
The association between an inflammation-based nutritional tool (Glasgow Prognostic Score) and length of hospital stay in patients with haematological cancer.
Background: This is a retrospective study to identify if Glasgow Prognostic Score (GPS) is associated with length of hospital stay (LOS) in haematological cancer.
Methods: The participants were adult inpatients at a single centre in between 2018 and 2022. Serum levels of CRP and albumin were measured at admission. GPS was calculated as follows: point "0" as CRP < 10 mg/L and albumin ≥ 35 g/L; point "2" as CRP ≥ 10 mg/L and albumin < 35 g/L; point "1" as either CRP ≥ 10 mg/L or albumin < 35 g/L. Patients with point "0" were classified as low risk whilst point "2" as high risk. LOS was defined as the interval between the admission and discharge date.
Results: As a result, the average age was 59.6 ± 12.6 years and the average LOS was 6.0 days (IQR = 2 days, 11 days). Of 1621 patients, 8.8% of them were high risk. GPS was associated with LOS (β = 2.7 days; 95% CI = 0.8 days, 4.6 days; p trend < 0.001) after full adjustment. Each point of GPS was associated with 1.9 days (95% CI = 1.4 days, 2.4 days) longer in LOS with full adjustment. The association was more prominent in younger patients (< 65 years), patients with leukaemia and myelodysplastic syndrome, and those with normal body weight status (18.5-24 kg/m2), compared with their counterparts.
Conclusion: GPS was associated with LOS in Chinese patients with haematological cancer, indicating GPS could be a useful tool to predict outcome.
期刊介绍:
Supportive Care in Cancer provides members of the Multinational Association of Supportive Care in Cancer (MASCC) and all other interested individuals, groups and institutions with the most recent scientific and social information on all aspects of supportive care in cancer patients. It covers primarily medical, technical and surgical topics concerning supportive therapy and care which may supplement or substitute basic cancer treatment at all stages of the disease.
Nursing, rehabilitative, psychosocial and spiritual issues of support are also included.