P A Fathima, Harish Kumar Shah, R S Aiswarya, P M Ajithlal, T V Shailaja, C Shubin, K J Reena, Prasanta Saini
{"title":"皮肤利什曼病：印度喀拉拉邦尼兰布尔部落人口中一种被忽视的临床表现。","authors":"P A Fathima, Harish Kumar Shah, R S Aiswarya, P M Ajithlal, T V Shailaja, C Shubin, K J Reena, Prasanta Saini","doi":"10.1093/trstmh/trae102","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Different clinical manifestations of leishmaniasis (cutaneous and visceral) caused by Leishmania donovani have been reported from Kerala, India. Leishmania donovani causing cutaneous leishmaniasis (CL) (also called atypical CL [ACL]) is one of the major health concerns in the Western Ghats belt of the state.</p><p><strong>Methods: </strong>Skin biopsies of 20 patients with suspected CL from Nilambur, Kerala, were processed for CL diagnosis during the period 2022-2023. Parasite species were characterized using Leishmania-specific Internal Transcribed Spacer-Ⅰ (ITS-Ⅰ) PCR and ITS-Ⅰ RFLP analysis.</p><p><strong>Result: </strong>A total of 18 cases were confirmed to be CL and the parasite was identified as L. donovani.</p><p><strong>Conclusion: </strong>These indigenous ACL (CL due to L. donovani) reports from the small foci of Nilambur reveal an emerging endemic zone of leishmaniasis in the Western Ghats.</p>","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cutaneous leishmaniasis: a neglected clinical manifestation among the tribal population in Nilambur, Kerala, India.\",\"authors\":\"P A Fathima, Harish Kumar Shah, R S Aiswarya, P M Ajithlal, T V Shailaja, C Shubin, K J Reena, Prasanta Saini\",\"doi\":\"10.1093/trstmh/trae102\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Different clinical manifestations of leishmaniasis (cutaneous and visceral) caused by Leishmania donovani have been reported from Kerala, India. Leishmania donovani causing cutaneous leishmaniasis (CL) (also called atypical CL [ACL]) is one of the major health concerns in the Western Ghats belt of the state.</p><p><strong>Methods: </strong>Skin biopsies of 20 patients with suspected CL from Nilambur, Kerala, were processed for CL diagnosis during the period 2022-2023. Parasite species were characterized using Leishmania-specific Internal Transcribed Spacer-Ⅰ (ITS-Ⅰ) PCR and ITS-Ⅰ RFLP analysis.</p><p><strong>Result: </strong>A total of 18 cases were confirmed to be CL and the parasite was identified as L. donovani.</p><p><strong>Conclusion: </strong>These indigenous ACL (CL due to L. donovani) reports from the small foci of Nilambur reveal an emerging endemic zone of leishmaniasis in the Western Ghats.</p>\",\"PeriodicalId\":23218,\"journal\":{\"name\":\"Transactions of The Royal Society of Tropical Medicine and Hygiene\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-11-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Transactions of The Royal Society of Tropical Medicine and Hygiene\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1093/trstmh/trae102\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Transactions of The Royal Society of Tropical Medicine and Hygiene","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/trstmh/trae102","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
Cutaneous leishmaniasis: a neglected clinical manifestation among the tribal population in Nilambur, Kerala, India.
Background: Different clinical manifestations of leishmaniasis (cutaneous and visceral) caused by Leishmania donovani have been reported from Kerala, India. Leishmania donovani causing cutaneous leishmaniasis (CL) (also called atypical CL [ACL]) is one of the major health concerns in the Western Ghats belt of the state.
Methods: Skin biopsies of 20 patients with suspected CL from Nilambur, Kerala, were processed for CL diagnosis during the period 2022-2023. Parasite species were characterized using Leishmania-specific Internal Transcribed Spacer-Ⅰ (ITS-Ⅰ) PCR and ITS-Ⅰ RFLP analysis.
Result: A total of 18 cases were confirmed to be CL and the parasite was identified as L. donovani.
Conclusion: These indigenous ACL (CL due to L. donovani) reports from the small foci of Nilambur reveal an emerging endemic zone of leishmaniasis in the Western Ghats.
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Transactions of the Royal Society of Tropical Medicine and Hygiene publishes authoritative and impactful original, peer-reviewed articles and reviews on all aspects of tropical medicine.
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