乌干达北部古卢地区转诊医院产前护理母亲中与妊娠期疟疾相关的因素。

IF 2.4 3区 医学 Q3 INFECTIOUS DISEASES
Solomon Oguta, Brian Serumaga, Lameck Odongo, Donald Otika, Jackline Ayikoru, Raymond Otim, Jimmyy Opee, Baifa Arwinyo, Francis Pebolo Pebalo, Vincentina Achora, Sande Ojara, Benard Abola, Silvia Awor
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引用次数: 0

摘要

背景:在乌干达,所有孕妇从妊娠 14 周起都要服用磺胺乙胺嘧啶(SP,Fansidar®)来进行妊娠期疟疾的假定性治疗,每四周一次,直到分娩。然而,产前母亲仍会感染疟疾。本研究旨在评估古卢地区转诊医院产前护理母亲中与妊娠期疟疾相关的因素:这是一项横断面研究,于 2023 年 7 月至 8 月在古卢地区转诊医院产前门诊进行。采用连续抽样法。采用访谈者发放的调查问卷收集社会人口学特征、体检结果和疟疾快速诊断检测(RDT)血样。快速诊断检测呈阳性即为孕期感染疟疾。数据在 STATA®15 中进行了预处理,并在 RStudio 4.2.2 中进行了逻辑回归分析。变量 p 结果:共招募了 350 名孕妇,其中 96% 的孕妇每天都睡在蚊帐里,超过半数(51.7%)的孕妇在本次怀孕期间尚未服用 SP(IPTp)。贫血患病率(Hb 结论:每十位母亲中就有四位感染了疟疾,贫血是一个风险因素,而受过高等教育则对妊娠期疟疾有保护作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Factors associated with malaria in pregnancy among antenatal care mothers at Gulu Regional Referral Hospital in northern Uganda.

Background: All pregnant mothers in Uganda are given sulfadoxine-pyrimethamine (SP, Fansidar®) for presumptive treatment of malaria in pregnancy from 14 weeks of gestation, every four weeks, until delivery. However, prenatal mothers still fall sick of malaria. This study aimed to assess the factors associated with malaria in pregnancy among antenatal care mothers at Gulu Regional Referral Hospital.

Methods: This was a cross-sectional study at Gulu Regional Referral Hospital antenatal clinic from July to August 2023. Consecutive sampling was used. An interviewer-administered questionnaire was used to collect sociodemographic characteristics, physical examination findings and blood samples taken for rapid diagnostic test (RDT) for malaria. A positive RDT was taken as the presence of malaria infection in pregnancy. Data was pre-processed in STATA®15, and logistic regression analysis was done in RStudio 4.2.2. Variables with p < 0.05 were taken as independently associated with malaria in pregnancy and reported as adjusted risk ratios (aRR).

Results: Three hundred fifty (350) pregnant women were recruited; 96% of them slept under mosquito nets daily, while more than half of them (51.7%) had not yet taken SP (IPTp) during their current pregnancy. Prevalence of anaemia (Hb < 11.0 g/dl) was 46.0%. Twenty-four per cent of the mothers were in the first trimester, 56.3% in the second and 19.7% in the third. The prevalence of malaria in pregnancy was 39.7% (95% CI 34.5-45.1%), equally distributed throughout the trimesters. Anaemia (aRR = 4.99, 95%CI 3.10-8.05, p < 0.001) and tertiary level of education (aRR = 0.29, 95% CI 0.14-0.62, p = 0.001) were significantly associated with malaria in pregnancy. Not sleeping under a mosquito net (aRR = 3.79, 95% CI 0.95-15.16, p = 0.059) may be a factor associated with malaria in pregnancy.

Conclusion: Four in every ten mothers had malaria infection, with anaemia being a risk factor, while a tertiary level of education was protective against malaria in pregnancy.

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来源期刊
Malaria Journal
Malaria Journal 医学-寄生虫学
CiteScore
5.10
自引率
23.30%
发文量
334
审稿时长
2-4 weeks
期刊介绍: Malaria Journal is aimed at the scientific community interested in malaria in its broadest sense. It is the only journal that publishes exclusively articles on malaria and, as such, it aims to bring together knowledge from the different specialities involved in this very broad discipline, from the bench to the bedside and to the field.
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