Arij Cheffai, Wiem Boufrikha, Rim Rakez, Amina Ben Ghechir, Mohamed Adnène Laatiri
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引用次数: 0
摘要
骨髓增生异常综合征（MDS）10%至20%的病例与自身免疫性疾病（AD）有关。克罗恩病（CD）并不是MDS常见的自身免疫表现。由MDS、CD和另一种自身免疫表现组成的三联症更为罕见。据我们所知，迄今为止，文献中仅报道过四例这种三联症病例，而我们的病例是第五例。这是一个 50 岁的男性病例，他有自身免疫性肝炎病史，五年后被诊断为 MDS 伴多线粒体发育不良。在确诊伴有 CD 的三周前，他开始服用阿扎胞苷。
An uncommon triad of myelodysplastic syndrome, Crohn's disease and autoimmune hepatitis: A case report and review of the literature
Myelodysplastic syndrome (MDS) is associated with an autoimmune disease (AD) in 10 to 20% of cases. Crohn's disease (CD) is not a common autoimmune manifestation reported with MDS. The triad made up of MDS, CD and another autoimmune manifestation is even more unusual. To our knowledge, only four cases with this triad have been reported in the literature to date, and ours is the fifth. It's about a 50-year-old man with a history of autoimmune hepatitis who was diagnosed, five years later, with MDS with multilineage dysplasia. He was started on Azacitidine three weeks before retaining the diagnosis of an associated CD.
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