A rare case report: Pott's Puffy tumor and Lemierre's syndrome with intracranial complications in an adult male

Pott Puffy Tumor (PPT) is extremely rare, yet potentially severe condition characterized by osteomyelitis of the frontal bone associated with one or multiple subperiosteal abscesses, primarily from nasosinusitis. It is characterized by localized frontal swelling accompanied by a subperiosteal abscess. Clinicians and radiologists do not widely recognize this complication of frontal sinusitis and, hence it is likely to be overlooked in clinical practice.

We describe, through this article, a unique case of frontal osteomyelitis in an immunocompromised patient, complicated by a subperiosteal orbital abscess, subdural empyema, intracerebral abscesses, superior sagittal sinus thrombosis, and pulmonary septic emboli, which also resulted in septic pulmonary infarcts, aligning with Lemierre's syndrome. Treatment included a combination of antibiotics and surgery, with careful monitoring for orbital and intracranial complications.